摘要
目的建立HPLC法测定莲连胶囊中延胡索乙素含量的方法。方法采用高效液相色谱法,以该胶囊中的延胡索乙素为定量指标,测定延胡索的含量。结果延胡索乙素在7.908～158.06μg/ml范围内峰面积具有良好的线性关系,平均回收率为96.18%,RSD为1.2%。结论建立的定量方法具有专属性好,准确、灵敏和可靠的特点,可用于莲连胶囊中延胡索乙素的含量测定及质量控制。
Objective To establish a HPLC method for tetrahydropalmatine in Lianlian capsule.Method The determination method of Lianlian capsule was carried out by HPLC,which quantitative index was represented with tetrahydropalmatine.Result The calibration curves was linear in the rage of 7.908～158.06 μg/ml for tetrahydropalmatine.The average recovery was 96.18 %（RSD 1.2%）.Conclusion The method was exclusive,accurate and reliable,which could be used for improvement of quality control in Lianlian capsule.
出处
《药学实践杂志》
CAS
2012年第5期376-377,383,共3页
Journal of Pharmaceutical Practice
