摘要
目的分析医院手术切口感染病原菌的分布及耐药性,从循证医学的角度探讨手术切口感染的预防及干预对策。方法回顾性调查医院手术切口感染患者的病案资料,细菌培养、鉴定按《全国临床检验操作规程》进行,药敏试验采用K-B法。结果 426株手术切口感染病原菌以革兰阴性杆菌为主,占60.56%,主要为铜绿假单胞、大肠埃希菌及鲍氏不动杆菌,占25.82%、13.15%及9.39%,其次是革兰阳性球菌,占36.15%,主要为金黄色葡萄球菌占23.00%,真菌占3.29%;病原菌均显示了较高的耐药性,耐甲氧西林金黄色葡萄球菌检出率为44.90%。结论医院手术切口感染病原菌主要以革兰阴性杆菌为主,其次是革兰阳性球菌及真菌,且病原菌耐药情况较为严峻;加强外科手术切口医院感染的监测工作,有针对性地采取相关措施,预防手术切口感染的发生。
OBJECTIVE To investigate the distribution and drug resistance of the pathogens causing surgical site infections（SSI） so as to provide the experimental evidence for prevention and intervention measures of SSI.METHODS Referring to National Guide to Clincal Laboratory Operations,the strains were isolated and identified.The antimicrobial susceptibility testing was performed by K-B methods.RESULTS Among totally 426 strains of pathogenic bacteria,the most were gram-negative bacilli（60.56%）,among which Pseudomonas aeruginosa（25.82%）,Escherichia coli（13.15%） and Acinetobacter baumannii（9.39%） were the predominant pathogens,the gram-positive cocci accounted for 36.15%,among which Staphylococcus aureus（23.00%） was predominant pathogen,and fungi accounted for 3.29%;the susceptibility testing results indicated that the most strains were highly resistant to antibiotics,and the detection rate of methicillin-resistant S.aureus（MRSA） was 44.90%.CONCLUSION The main pathogenic bacteria causing SSI are gram-negative bacilli,followed by the gram-positive cocci and fungi;to strengthen the monitoring of SSI and take corresponding measures appropriately can prevent the SSI.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第19期4387-4389,共3页
Chinese Journal of Nosocomiology
关键词
手术切口
感染
病原菌
耐药性
Surgical incision
Nosocomial infection
Pathogens
Antibiotics resistance
