摘要
目的观察生血宁片联合鲨肝醇对抗结核药致白细胞减少的疗效。方法将72例抗结核治疗后白细胞减少的初治肺结核患者随机分为治疗组和对照组各36例,治疗组给予生血宁片联合鲨肝醇治疗,对照组仅给予鲨肝醇治疗,两组疗程均为14d,比较治疗前后两组白细胞指标的变化。结果两组患者临床症状及白细胞指标变化情况均明显,但总有效率治疗组为97.2%,对照组为83.3%,两组比较差异有统计学意义(P<0.05)。且治疗后治疗组白细胞变化情况较对照组明显,两组比较差异有统计学意义(P<0.05)。结论生血宁片联合鲨肝醇可以有效治疗抗结核药所致白细胞减少。
Objective To observe the effect of Shengxuening and Batilol on leukopenia induced by antituberculosis drugs. Methods 72 pulmonarY tuberculosis patients whose white blood cell had been decrease due to antituberculosis drugs were separated into two groups randomly, with each group of 36 cases. The patients of treatment group were treated by Shengxuening and Batilol. The patients of control group were treated only by Batilol. The course of treatment of treatment group and control group were both 14 days. White blood cells indicators of two groups before and after treatment were compared. Results It had changed significantly that clinical symptom and the change of index on white blood cell of all the patients. The total effective rate of treatment group was 97.2% and it was 83.3% in control group. The total effective rate between the two groups were significant difference （P 〈 0.05）.It changed more obviously in treatment group than it in control group that the change of index on white blood cell （P 〈 0.05）. Conclusion Shengxuening tablet combined Batilol can be an effective treatment for leukopenia induced by antituberculosis drugs.
出处
《中国医药科学》
2012年第19期61-62,共2页
China Medicine And Pharmacy
关键词
生血宁
鲨肝醇
结核
白细胞减少
Shengxuening
Batilol
Tuberculosis
Leukopenia
