期刊文献+

降低我国艾滋病患者病死率的几个关键措施 被引量:5

Critical issues for decreasing the mortality of human immunodeficiency virus/acquired immunodeficiency syndrome patients in China
下载PDF
导出
摘要 随着人类免疫缺陷病毒(HIV)感染者逐渐进入获得性免疫缺陷综合征(AIDS)期,我国HIV感染者病死人数逐渐增加,已超过结核病与狂犬病的病死人数,位居第1。如何降低HIV/AIDS患者的病死率是我国目前亟待解决的重要课题。针对我国HIV/AIDS患者的特点,应采用多种措施。其中关键为:落实患者对药物的依从性,优化抗病毒治疗方案;扩大抗病毒治疗覆盖面,以增加接受抗病毒治疗的患者;加大检测力度,早诊断和早治疗以延长患者寿命,改善预后;注意对患者并发症的治疗,并科学分析病死原因。这些措施的实施需要社会各界共同参与和努力。 As human immunodeficiency virus (HIV)-infected patients gradually progressed to acquired immunodeficiency syndrome (A1DS) these years, the lethal cases of HIV patients have increased markedly, and have surpassed the mortality of tuberculosis and rabies, ranking first among all mandatory reporting infectious diseases. Decreasing the mortality of HIV/AIDS patients is one of the big challenges we are facing. The following issues are critical: strengthen strict adherence to antiretroviral therapy (ART) among patients, increase new kinds of drugs to facilitate expanding ART coverage, encourage HIV screening for early diagnosis and early ART and comprehensive treatment of complications. The implementation of these interventions needs efforts from different disciplines.
作者 卢洪洲 陈军
出处 《微生物与感染》 2012年第3期142-145,共4页 Journal of Microbes and Infections
基金 "十二五"国家科技重大专项(2012ZX10001003)
关键词 艾滋病 治疗 病死率 Acquired immunodeficiency syndrome Therapy Mortality
  • 相关文献

参考文献20

  • 1Ministry of Health of the People's Republic of China. 2012 China AIDS Response Progress Report [R/OL]. Beijing, Ministry of Health of the People's Republic of China, 2012. http://www, unaids, org/en/dataanalysis/knowyour- response/countryprogressreports/2012countries/ce CN Narra- tive_Report% 5B1% 5D. pelf. 被引量:1
  • 2中华人民共和国卫生部.2011年度全国法定传染病报告发病、死亡统计表[EB/0L].http://www.moh.gov.cn/pub-licfiles/business/htmlfiles/mohjbyfkzj/s3578/201202/54106.htm. 被引量:1
  • 3Zhang F, Dou Z, Ma Y, Zhang Y, Zhao Y, Zhao D, Zhou S, Bulterys M, Zhu H, Chert RY. Effect of earlier in- itiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national ob- servational cohort study [J]. Lancet Infect Dis, 2011, 11 (7) :516-524. 被引量:1
  • 4Zhang Y, Dou Z, Sun K, Ma Y, Chen RY, Bulterys M, Zhao Y, Zhu H, Liu Z, Zhang F. Association between missed early visits and mortality among patients of China na- tional free antiretroviral treatment cohort [J]. J Acquir Im- mune Defic Syndr, 2012,60(1) : 59-67. 被引量:1
  • 5陈军,张仁芳,郑毓芳,刘莉,潘承恩,卢洪洲.高效抗反转录病毒治疗一线方案的安全性和耐受性研究[J].中华临床感染病杂志,2009,2(3):139-142. 被引量:3
  • 6Nakagawa F, Lodwick RK, Smith CJ, Smith R, Cambiano V, Lundgren JD, Delpech V, Phillips AN. Projected life expectancy of people with HIV according to timing of diag- nosis [J]. AIDS, 2012,26(3):335-343. 被引量:1
  • 7Severe P, Juste M.A, Ambroise A, Eliacin L, Marchand C, Apollon S, Edwards A, Bang H, Nicotera J, Godfrey C, Gulick RM, Johnson WD Jr, Pape JW, Fitzgerald DW. Early versus standard antiretroviral therapy for H1V-infec- ted adults in Haiti [J]. N Engl J Med, 2010, 363(3): 257-265. 被引量:1
  • 8When To Start Consortium, Sterne JA, May M, Costagliola D, de Wolf F, Phillips AN, Harris R, Funk MJ, Geskus RB, Gill J, Dabis F, Miro JM, Justice AC, Ledergerber B, Faitkenheuer G, Hogg RS, Monforte AD, Saag M, Smith C, Staszewski S, Egger M, Cole SR. Timing of initiation of antiretroviral therapy in AIDS-free HIV-l-infected pa- tients.- a collaborative analysis of 18 HIV cohort studies [J]. Lancet, 2009,373(9672) :1352-1363. 被引量:1
  • 9World Health Organization. Rapid advice antiretroviral therapy for HIV infection in adults and adolescents. Gene- va, 2009 [EB/OL]. http://www, who. int/hiv/pub/arv/rapid_advice_art, pdf. 被引量:1
  • 10Department of Health and Human Services Panel on An- tiretroviral Guidelines for Adults and Adolescents. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-l-in- fected adults and adolescents VEB/OL3. In: Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents. 2012. http://www, aidsinfo, nih. gov/content files/lvguidelines/adultandadolescentgl, pdf. 被引量:1

二级参考文献15

  • 1王维真.我国艾滋病的流行形势与防治对策[J].中国护理管理,2005,5(6):9-11. 被引量:10
  • 2王爱霞,王福生,王清玥,王健,冯铁建,卢洪洲,孙洪清,孙永涛,叶寒辉,李太生,李兴旺,刘正印,邢玉兰,何云,汪宁,吴昊,吴南屏,张福杰,周曾全,宫恩聪,赵红心,赵敏,唐小平,徐莲芝,徐小元,曹韵贞,康来仪,蒋岩,蔡卫平,樊庆泊,潘孝彰.艾滋病诊疗指南[J].中华传染病杂志,2006,24(2):133-144. 被引量:631
  • 3刘水腾,陆普选,周亚红,赖伟珍,刘艳,徐岩,童新灯,唐奇远,李健.20例艾滋病死亡原因分析[J].实用预防医学,2007,14(1):86-87. 被引量:11
  • 4Onyaneha OB, Oeholla DN. An imformetrie investigation of the related- ness of opportunistic infections to HIV/AIDS[ J]. Inform Proc Manag, 2005,41 (6) :1573 - 1588. 被引量:1
  • 5Bonnet F, Lewden C, May T, et al. Opportunistic infections as causes of death in HIV-infected patients in the HAART era in France [ J ]. Stand J Infect Dis,2005,37(6 -7) :482 -487. 被引量:1
  • 6Chariyalertsak S, Sirisanthana T, Saengwonloey O, et al. Clinical presentation and risk behaviors of patients with acquired immunodeficieney syndrome in Thailand, 1994-1998: regional variation and temporal trends[ J]. Clin Infect Dis,2001,32(6) :955 -962. 被引量:1
  • 7Aldaz P,Moreno-Iribas C,Egüés N,et al.Mortality by causes in HIV-infected adults:comparison with the general population[J].BMC Public Health,2011,11:300. 被引量:1
  • 8Jabs DA,Holbrook JT,Van Natta ML,et al.Risk factors for mortality in patients with AIDS in the era of highly active antiretmviral Therapy[J].Ophthalmology,2005,112(5):771-779. 被引量:1
  • 9Puhan MA,Van Natta ML,Palella FJ,et al.Ocular Complications of AIDS Research Group.Excess mortality in patients with AIDS in the era of highly active antiretroviral therapy:temporal changes and risk factors[J].Clin Infect Dis,2010,51(8):947-956. 被引量:1
  • 10Parczewski M,Bander D,Leszczyszyn-Pynka M,et al.Risk of All-Cause mortality in HIV infected patients is associated with clinical,immunologic predictors and the CCR5 Δ32 Deletion[J].PLoS One,2011,6(7):e22215. 被引量:1

共引文献19

同被引文献53

  • 1杨帆,祝晓莲,王维.艾滋病防治的政策研究[J].国际技术经济研究,2004,7(3):11-16. 被引量:12
  • 2李在村,吴昊.HIV/AIDS患者贫血的研究进展[J].国外医学(流行病学.传染病学分册),2004,31(6):351-353. 被引量:23
  • 3范霞,赵彬,刁莹莹,尚红.HIV感染者β2微球蛋白及其他临床免疫指标的研究[J].中华检验医学杂志,2007,30(1):59-60. 被引量:7
  • 4本书编写组.国家免费艾滋病抗病毒药物治疗手册[M].3版.北京:人民卫生出版社,2012. 被引量:10
  • 5米丰.我国艾滋病防治工作进展情况[J].中国青年研究,2013(4):118-118. 被引量:3
  • 6Nguyen N, Holodniy M. HIV infection in the elderly [J]. Clinical interventions in aging, 2008, 3 (3): 453 - 472. 被引量:1
  • 7Bastard M, Soulinphumy K, Phimmasone P, et al. Women experience a better long-term immune recovery and a better survival on HAART in Lao People's Democratic Republic [ J ]. BMC infectious diseases, 2013, 13 : 27. Published online Jan 22,2013. doi: 10. 1186/1471 - 2334 - 13 - 27. 被引量:1
  • 8Kwesigabo G, Killewo JZ, Urassa W, et al. Monitoring of HIV- 1 infection prevalence and trends in the general population using pregnant women as a sentinel population :9 years experience from the Kagera region of Tanza- nia[J]. J Acquit Immune Deftc Syndr, 2000,23 (5) :410-417. 被引量:1
  • 9McDonald AM, Li ~, Dore GJ, et al. Late I-IIV presentation among AIDS cases in Australia, 1992-2001 [J]. Aust N Z J Public Health, 2003,27 (6) : 608-613. 被引量:1
  • 10Pisani E, Lazzari S ,Walker N, et al. HIV surveillance :a global perspec- tive[J]. J Acquit Immune Defle Syndr,2003,32 Suppl 1 :$3-11. 被引量:1

引证文献5

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部