摘要
目的探讨Tei指数(TI)在评估妊娠期高血压疾病(HDCP)胎儿心功能的临床价值。方法 HDCP孕妇根据高血压严重程度分为妊娠期高血压组、子痫前期轻度组及子痫前期重度组,正常孕妇为对照组;通过测量胎儿左、右心室相应的时间间期,计算胎儿左、右心室TI;采用方差分析比较各组间胎儿左、右心室TI的差异性。结果子痫前期轻度组胎儿右心室TI高于对照组,差异有统计学意义(P<0.05);子痫前期重度组胎儿左、右心室TI分别高于对照组,差异具统计学意义(分别为P<0.05与P<0.01);将各组中宫内生长受限(IUGR)胎儿剔除后,仅子痫前期重度组胎儿右心室TI高于对照组(P<0.05)。结论子痫前期可引起胎儿心功能异常,IUGR的出现提示胎儿心功能异常发展到严重阶段,是预后不良的标志。
Objective To evaluate the clinical value of Tei index in assessment of the cardiac function of fetuses in hypertensive dis- orders complicating pregnancy. Methods According to the severity the hypertension, hypertensive disorders complicating pregnancy women were divided into gestational hypertension group, mild pre - eclampisa group and severe pre - eclampsia group. The corresponding time intervals of fetuses ventricular were measured, and Tei index were calculated. Analysis of variance was used to compare the difference of fetuses TI among four groups and in the four groups,intrauterine growth restriction （IUGR） fetuses were eliminated. Results Left ven- tricular Tei index（ LV - TI） and right ventricular Tel index（ RV - TI） in severely pre - eelampsia group were obviously higher than those in control group （ P 〈 0.05 and P 〈 0.01, respectively）. RV - TI in mild pre - eclampsia group were higher than those in control group （P 〈 0.05 ）. And in the four groups, （ IUGR fetuses were eliminated） only RV - TI in severely pre - eclampsia group were higher than those in control group （P 〈 0.05）. Conclusion Pre - eclampsia can endanger the eardiaer function of the fetuses. Onset of IUGR among HDCP fetuses infer severely impaired fetuses cardiac function and noor fetuses prognosis.
出处
《医学研究杂志》
2012年第9期146-149,共4页
Journal of Medical Research
基金
温州市瓯海区科技局科技计划项目(20110171)
关键词
TEI指数
胎儿心功能
妊娠并发症
心血管
高血压
宫内生长受限
Tel index
Fetal cardiac function
Pregnancy complications
Cardiovascular
Hypertension
Intrauterine growth restriction
