摘要
羊膜腔感染是包括羊水、胎膜 (绒毛膜、羊膜 )、胎盘的感染和 (或 )临产前、产时发生的子宫感染。约 30 %的早产与羊膜腔感染有关。近年研究表明 ,早产伴羊膜腔感染患者的胎膜、胎盘、羊水和下生殖道分泌物中前列腺素、细胞因子浓度升高 ,提示其可能机制为 :妊娠晚期微生物通过多种途径侵入羊膜腔 ,刺激妊娠组织产生大量细胞因子 ,后者又加速前列腺素的合成与释放 ,从而引起宫颈成熟 ,子宫收缩 ,导致早产。
WT5”BZ]Intraamniotic infection (IAI) is the infection of amniotic fluid,fetal membranes,placenta and/or the infection of uterus happening before or in labor.IAI is responsible for about 30% premature labor.Recent studies indicate that elevated prostaglandin and cytokine levels of amniotic fluid,fetal membranes and lower genital tract fluid associated with IAI among women who delivered prematurely.These results support the hypothesis that infection induced premature labor proceeds by a mechanism involving the stimulating of cytokine production followed by prostaglandin release which leading to cervical ripening and uterine contraction.Those patients with confirmed IAI or premature preterm rupture of membrane benefit from antibiotic treatment. [WT5”HZ]
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2000年第4期186-189,共4页
Journal of Practical Obstetrics and Gynecology
关键词
早产
羊膜腔感染
前列腺素
细胞因子
Premature labor
Intraamniotic infection
Prostaglandin
Cytokine
