摘要
目的:探讨IL-6、IL-8、TNF-α在胎膜早破早产孕妇血清及羊水中的含量与胎膜早破早产的关系。方法:采用酶联免疫吸附法测定胎膜早破早产孕妇(早产组)20例与正常孕妇(对照组)20例血清及羊水中的IL-6、IL-8、TNF-α的含量。结果:早产组母血清及羊水中IL-6、IL-8、羊水TNF-α水平均较对照组高(P<0.05)。早产组绒毛膜羊膜炎者血清、羊水中IL-6、IL-8水平高于非绒毛膜羊膜炎者(P<0.05)。结论:孕妇血清、羊水中IL-6、IL-8水平与感染引起的早产有相关关系。
Objective： To investigate the relationship between the levels of interleukin -6 （IL -6）, interleukin -8 （IL -8 ）, tumor necrosis factor -α （TNF-α） in serum and amniotic fluid of preterm women with premature rupture of membranes. Methods： The levels of IL - 6, IL - 8, TNF-α in serum and amniotic fluid were detected in 20 cases with premature rupture of membranes （ premature group） and 20 cases of normal pregnancy （contral group） by enzyme -linked immunosorbent assay （ELISA） . Results： The levels of IL - 6, IL - 8 in serum and IL - 6, IL - 8, TNF-α in amniotic fruid in premature group were significantly higher than those in contral group （ P 〈 0. 05）. In premature group, the levels of IL - 6, IL - 8 in serum and amniotie fluid of women with chofioamnlonitis were significantly higher than those of women without chorioamnionitis （ P 〈 0. 05） . Conclusion： The levels of IL - 6, IL - 8 in serum and amniotic fluid of the pregnant women are associated with the onset of preterm labor caused by infection.
出处
《中国妇幼保健》
CAS
北大核心
2008年第35期4995-4997,共3页
Maternal and Child Health Care of China
关键词
IL-6
IL-8
TNF-α
胎膜早破
早产
Interleukin - 6
Interleukin - 8
Tumor necrosis factor -α
Premature rupture of membranes
Premature delivery
