摘要
目的研究中年人内脏脂肪含量与2型糖尿病的相关性。方法选取上海市淞南社区40～60岁血糖正常者（221例）、糖耐量异常者（213例）、2型糖尿病患者（135例）共569例作为研究对象，进行问卷调查、体格检查，测定其血糖、血脂等生化指标，行CT及FATSCAN软件测量腹部内脏脂肪及腹部皮下脂肪面积。结果随糖代谢异常严重程度增加，内脏脂肪面积呈递增趋势（P〈0．05）。内脏脂肪面积与糖、脂质代谢指标明显相关（P〈0．05）。Logistic多元回归分析显示内脏脂肪含量是2型糖尿病的独立危险因素，内脏脂肪面积每增加1个标准差，2型糖尿病的患病风险增加0．438倍。结论中年人内脏脂肪堆积能够增加2型糖尿病的患病风险。
Objective To investigate the relationship between visceral fat area and type 2 diabe- tes in middle-aged people. Methods 569 cases aging 40 to 60 years from Songnan community of Shang- hai ,including people with normal blood glucose （221 cases）, people with pre-diabetes （213 cases ） and type 2 diabetes patients （ 135 cases）, were conducted to accept questionnaire interview, physical examina- tion and blood sample biochemical test. CT and FATSCAN software were used to measure abdominal vis- ceral fat area and subcutaneous fat area. Results Visceral fat area was increased with the severity of dis- orders of glucose metabolism（P 〈0.05 ）. Visceral fat area was significantly correlated with glycemia and lipidemia（ P 〈 0.05 ）. With visceral fat area increasing per one standard deviation, the risk of type 2 dia- betes increased 0. 438 times. Conclusion Visceral fat is the independent risk factor of type 2 diabetes. Visceral fat accumulation in middle-aged people can increase the prevalence of type 2 diabetes.
出处
《临床内科杂志》
CAS
2012年第7期469-471,共3页
Journal of Clinical Internal Medicine
基金
基金项目：国家自然科学基金资助项目（81170739、30900700、81170719）
上海市自然科学基金资助项目（10ZR1426400）
上海市科委专项课题（10140902900）
浦江人才计划（10P11408900）
关键词
内脏脂肪含量
2型糖尿病
中年人
Visceral fat area
Type 2 diabetes
Middle-aged people
