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条件复制腺病毒Ad—MK联合丝裂霉素对膀胱癌细胞的作用 被引量:5

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摘要 条件复制腺病毒指在正常细胞内无复制或杀伤作用,而在同一机体内的肿瘤细胞中可选择性复制和溶解之,细胞裂解后释放的子代病毒颗粒又感染邻近的肿瘤细胞,如此不断循环反复增殖从而达到杀灭癌细胞的肿瘤特异性增殖型病毒。本实验旨在观察该病毒单独及联合化疗后对膀胱癌细胞的作用。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第8期1633-1633,共1页 Chinese Journal of Experimental Surgery
基金 河北省医学科学重点指令性课题(20090029)
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  • 1李昕,朱步东.中期因子与肿瘤[J].国外医学(肿瘤学分册),2005,32(10):745-748. 被引量:1
  • 2Adachi Y, Matsubara S, Pedraza C, et al. Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1) [J]. Oncogene,1996,13(10) :2197 -2203. 被引量:1
  • 3Garver RI, Chan CS, Milner PG. Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues[J]. Am J Respir Cell Mol Biol, 1993,9(5) :463 --466. 被引量:1
  • 4Garver RI, Radford DM, Donis - Keller H, et al. Midkine and pleiotrophin expression in normal and malignant breast tissue[J]. Cancer, 1994,74(5) :1584- 1590. 被引量:1
  • 5Kaname T, Kadomatsu K, Aridome K, et al. The expression of truncated MK in human tumors [ J ]. Biochem Biophys Res Commun, 1996,219 ( 1 ) :256 - 260. 被引量:1
  • 6Miyauchi M, Shimada H, Kadomatsu K, et al. Frequent expression of midkine gene in esophageal cancer suggests a potential usage of its promoter for suicide gene therapy [J]. J Cancer Res, 1999,90(4) :469 -475. 被引量:1
  • 7Ye C, Qi M, Fan QW, et al. Expression of midkine in the early stage of carcinogenesis in human colorectal cancer[ J]. Br J Cancer, 1999,79( 1 ) : 179 - 184. 被引量:1
  • 8O'Brien T, Cranston D, Fuggle S, et al. The angiogenic factor midkine is expressed in bladder cancer, and overexpression correlates with a poor outcome in patients with invasive cancers[J]. Cancer Res, 1996,56( 11 ) :2515 - 2518. 被引量:1
  • 9Muramaki M, Miyake H, Hara I, et al. Introduction of midkine gene into human bladder cancer cells enhances their malignant phenotype but increase their sensitivity to antiangiogenic therapy [ J ]. Clin Cancer Res, 2003, 9 (14) :5152 -5160. 被引量:1
  • 10Ikematsu S, Yano A, Aridome K, et al. Serum midkine levels are increased in patients with various types of carcinomas[J]. Br J Cancer, 2000,83(6) :701 -706. 被引量:1

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  • 1杨建萍,李晟磊,赵志华,张红新,丁胭脂,张虎,陈奎生.雷帕霉素及mTOR siRNA对宫颈癌HeLa细胞mTOR和4EBP1表达的影响[J].肿瘤防治研究,2014,41(1):40-45. 被引量:3
  • 2吴晓鹏,刘孝民,刘勤,郭艳珍.三氧化二砷联合紫杉醇对A549细胞增殖和裸鼠异位肿瘤生长的影响[J].中国生化药物杂志,2014,34(4):66-69. 被引量:3
  • 3Xu C,Sun Y, Wang Y, et al. CEA promoter-regulated oncolytic adeno- virus-mediated Hsp70 expression in immune gene therapy for pancre- atic cancer. Cancer Lett ,2012,319 : 154-163. 被引量:1
  • 4Diaconu I, Cerullo V, Hirvinen ML, etal. Immune response is an im- portant aspect of the antitumor effect produced by a ClMOL-encoding oncolytic adenovirus. Cancer Res,2012,72:2327-2338. 被引量:1
  • 5Chen Z, Liu N, Zhu G, et al. Targeting of the anti-apoptotic gene sur- vivin in human thyroid carcinoma, lnt J Mel Med ,2012,30:465-472. 被引量:1
  • 6Chen XQ,Yang S,Li ZY,et al. Effects and mechanism of downregula- tion of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells. Mol Med Report,2012,5:917-922. 被引量:1
  • 7Cao H, Hu Y, Wang P, et al. Down-regulation of Notch receptor signa- ling pathway induces caspase-dependent and caspase-independent ap- op/osis in lung squamous cell carcinoma cells. APMIS ,2012,120:441 - 450. 被引量:1
  • 8Majid AM,Ezelle H,SKah S,et al.Evaluating replication-defective ve-sicular stomatitis virus as a vaccine vehicle.J Virol,2006,80:6993-7008. 被引量:1
  • 9Diaz M,Ziemin S,Le BM,et al.Homozygous deletion of the alpha-andbeta 1-interferon genes in human leukemia and derived cell lines.ProcNatl Acad Sci U S A,1988,85:5259-5263. 被引量:1
  • 10Jemal A, Bray F, Center MM, et al. International variations in bladder cancer incidence and mortality [J]. Eur Urol,2014,66( 1 ) :59-73. 被引量:1

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