摘要
目的了解肿瘤住院病人麻醉药品和一类精神药品使用情况,为临床合理用药提供依据。方法调查2010年1～12月住院病人麻醉药品和一类精神药品处方13926张,采用世界卫生组织推荐的限定日剂量(DDD)和药物利用指数(DUI)进行统计、分析。结果用药频度最大的为枸橼酸芬太尼注射液,主要用于手术镇痛;用于癌症疼痛治疗以盐酸布桂嗪注射液用药频度最大,硫酸吗啡控、缓释片次之。注射剂如盐酸布桂嗪注射液、盐酸哌替啶注射液、盐酸吗啡注射液的DUI均小于1;而口服制剂盐酸羟考酮控释片,盐酸布桂嗪片,硫酸吗啡控、缓释片的DUI均大于1。结论癌症疼痛第三阶梯用药主要以口服吗啡为主,基本符合WHO的要求;但第二阶梯用药以盐酸布桂嗪注射液用药频度最大,不甚合理。
Objective To investigate the use of narcotic drugs and psychotropic drugs of category I for tumor hospital inpatients and provide basis for clinical rational drug use.Methods A total of 13926 prescriptions of narcotic drugs and psychotropic drugs of category I between January and December in 2010 were included in the study.The WHO-recommended defined daily dose method（DDD method） and drug utilization index（DUI） were used for the statistical analysis.Results For operative analgesia,fentanyl citrate injection had the highest medication frequency（DDDs）,while for relieving cancer pain;Bucinnazine Hydrochloride Injection had the highest frequency of drug use,followed by Morphine Sulfate Controlled/Sustained-release Tablets.The DUI of injections such as Bucinnazine Hydrochloride Injection,Pethidine Hydrochloride Injection,Morphine Hydrochloride Injection were less than 1,and as to oral preparations such as Oxycodone Hydrochloride Controlled-release Tablets,Bucinnazine Hydrochloride Tablets,Morphine Sulfate Controlled/Sustained-release Tablets,the DUI were higher than 1.Conclusion The drugs used for the third step therapy of the cancer pain mainly dominated by oral morphine,broadly in line with WHO requirements,while in the second step medication,Bucinnazine Hydrochloride Injection was put into use most frequently,which was not very reasonable.
出处
《中国药事》
CAS
2012年第7期782-786,共5页
Chinese Pharmaceutical Affairs
关键词
麻醉药品
一类精神药品
癌症疼痛
处方分析
narcotic drugs； psychotropic drugs of category Ⅰ； cancer pain； analysis of the prescriptions
