摘要
[目的]探讨抑制素A、激活素A在预测先兆流产妊娠结局中的作用.[方法]选择妊娠6～11周的孕妇1000例,随访至孕13周,选择其中先兆流产发展为难免流产者40例（A组）,出现先兆流产但经过干预后继续妊娠者75例（B组）,正常妊娠者681例（C组）,采用ELISA法检测并比较三组孕妇血清抑制素A与激活素A的浓度.[结果]A组孕妇抑制素A及激活素A浓度显著低于B族和C组,差异有显著性（P〈0.01）;B组孕妇抑制素A及激活素A浓度稍低于C组,但差异无显著性（P〉0.05）.[结论]抑制素A与激活素A可以作为预测先兆流产妊娠结局的良好标记物.
[Objective]To explore the role of inhibin A and activin A in the prediction of the pregnancy outcome of threatened abortion. [Methods] Totally 1000 pregnant women with 6-10 weeks of pregnancy were selected and followed up to 13 weeks after pregnancy. Group A were 40 pregnant women with inevitable abor-tion developed from threatened abortion. Group B were 75 continuous pregnant women after intervention of threatened abortion. Group C were 681 normal pregnant women. Serum inhibin A and activin A of pregnant women among three groups were detected by ELISA and compared. [Results] Serum inhibin A and aetivin A in group A were markedly lower than those in group B and group C, and there were significant differences（ P〈0.01）. Serum inhibin A and activin A in group t3 were slightly lower than those in group C, and there were significant differences（ P〉0.05）. [Conclusion]Inhibin A and aetivin A can be used as good markers for pre-dicting the pregnancy outcome of threatened abortion.
出处
《医学临床研究》
CAS
2012年第5期835-837,共3页
Journal of Clinical Research
基金
湖南省科技厅项目（项目编辑：2009FJ3185）
