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血清抑制素A检测在子痫前期监测中的作用 被引量:1

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摘要 目的 探讨孕妇血清抑制素A检测在子痫前期监测中的作用.方法 选择单胎初产妇462例,根据妊娠结局将其分为子痫前期组(n=36)和正常妊娠组(n=426),上述孕妇均在孕24~28周、孕28~34周2个时间段采集清晨空腹静脉血,分离血清.采用连续两步酶联免疫顺磁性微粒化学发光法(夹心法)测定血清抑制素A,检测下限为1 pg/mL,总不精密度小于5%.结果 孕24~28周,子痫前期组孕妇血清抑制素A浓度为(834.5±361.2)pg/mL,明显高于正常妊娠组[(396.6±212.3)pg/mL];孕28~34周,子痫前期组孕妇血清抑制素A浓度为(1 033.6±377.2)pg/mL,明显高于正常妊娠组(526.7±261.7)pg/mL],差异均有统计学意义(P〈0.05).两组孕妇血清抑制素A浓度随妊娠进展逐渐升高.结论 孕妇血清抑制素A的测定对子痫前期的预警具有积极意义.
出处 《国际检验医学杂志》 CAS 2013年第21期2913-2914,共2页 International Journal of Laboratory Medicine
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