摘要
目的比较齐拉西酮和利培酮治疗老年期精神分裂症的疗效及不良反应。方法将86例老年期精神分裂症患者随机分为两组,分别用齐拉西酮与利培酮治疗12周。采用阳性症状与阴性症状量表(PANSS)评定临床疗效,治疗中出现的症状量表(TESS)评定不良反应。结果齐拉西酮与利培酮治疗12周有效率分别为88.37%和90.70%,疗效差异无显著性(P>0.05)。结论齐拉西酮与利培酮治疗老年期精神分裂症的疗效相当,但不良反应有所不同。
Objective To investigate the clinical efficacy and side effect of ziprasidone in the treatment of senile schizophrenia compared with risperidone.Method A total of 86 patients with senile schizophrenia were divided into two groups randomly,treated with ziprasidone and risperidone respectively for 12 weeks.the Positive and negative symptom scale（PANSS）and treatment emergent symptoms scale（TESS）were used to assess the therapeutic effect and side effect respectively.Results The effective rate of ziprasidone group and risperidone group were 88.37% and 90.70% respectively.There were not significant differences between two groups in improvement rate and side effect（P〉0.05）.Conclusion Ziprasidone is an effective drug with light side effects in the treatment of senile schizophrenia.
出处
《中国健康心理学杂志》
2012年第5期663-664,共2页
China Journal of Health Psychology
