摘要
采用Ｗｉｓｔａｒ大鼠５０只分别饮用含氟化钠１５０ｍｇ／Ｌ和含氟化钠１５０ｍｇ／Ｌ加不同剂量亚硒酸钠水。二个月后断头处死，取肺，脾作肥大细胞（ＭＣ），糖元ＰＡＳ反应，ＤＮＡ（Ｆｅｕｌｇｅｎ）反应观察。结果：肺，脾氟化钠（１５０ｍｇ／Ｌ）组肥大细胞与正常组比较，无明显变化。糖元ＰＡＳ反应，ＤＮＡ（Ｆｅｕｌｇｅｎ）反应减弱；氟化钠（１５０ｍｇ／Ｌ）加亚硒酸钠（２．０ｍｇ／Ｌ）组，肥大细胞显著增加，糖元ＰＡＳ反应，ＤＮＡ（Ｆｅｕｌｇｅｎ）反应程度增强。提示：硒在保护氟引起肺，脾损伤过程中，可能对肺、脾的肥大细胞增生和活化起促进作用。
The rats,treated with NaF 150mg/L and different concetration of selenium,were decopitated after two months. The results showed:the quantity changes of mast cells were not clear compares that in group NaF with that normal group. The glycogen PAS,DNA (Feulgen) reaction were weakened. On the other hand,in group Se2.0mg/L, the mast cell,the glocogen PAS,DNA (Feulgen) reaction increased obviously. The results demonstrate that Se2.0mg/ L might promote function of proliferation and activity for mast cell of lungs and spleens in protecting lung and spleen infured by fluoride 150mg/L.
出处
《黄石高等专科学校学报》
2000年第1期29-32,共4页
Journal of Huangshi Polytechnic College
关键词
肥大细胞
硒
氟
DNA反应
肺损伤
脾损伤
Mast cell
the glycogen PAS
DNA(Feulgen)
Proliferation
activity
