摘要
目的:探讨机械通气治疗急性呼吸窘迫综合征的疗效。方法:将2008年12月-2011年12月笔者所在医院收治的50例急性呼吸窘迫综合征患者随机分为观察组和对照组,每组25例,两组均给予基础治疗,其中对照组采用传统机械通气治疗,观察组采用肺保护性通气,比较两组的治疗效果、呼吸相关炎症(VAP)发生率、带机时间、病死率。结果:两组患者治疗后PaO2和PaCO2较治疗前均有明显改善(P<0.05),治疗后两组两项指标比较差异无统计学意义(P>0.05)。观察组带机时间、VAP发生率和病死率分别为(5.6±1.6)d、20%(5/25)、8%(2/25),明显优于对照组(8.2±1.3)d、32%(8/25)、20%(5/25)(P<0.05)。结论:机械通气可以快速缓解患者的缺氧症状,采用肺保护性通气治疗较传统机械通气治疗效果更好,能减少并发症,降低死亡率。
Objective：To study the clinical effect of mechanical ventilation treatment on acute respiratory distress syndrome（ARDS）.Methods：From December 2008 to December 2011,50 cases with ARDS were randomly divided into control group and observation group.Each group included 25 case,using basic therapy.The control group were treated with traditional mechanical ventilation,while the observation group were used lung protective ventilation.Therapeutic efficacy,incidence rate of ventilator-associated pneumonia（VAP）,the using time of mechanical ventilation and fatality were compared between two groups.Results：Both groups were found the PaO2 and PaCO2 after treatment significantly improved than that before treatment（P0.05）,the different of PaO2 and PaCO2 after treatment between two groups didn＇t show the significant（P0.05）.The data for the using time of mechanical ventilation,rat of VAP,fatality of the control group were（5.6±1.6）d,20%（5/25）,8%（2/25）,which were better than the experience group（8.2±1.3）d,32%（8/25）,20%（5/25）（P0.05）.Conclusion：The use of mechanical ventilation for ARDS can relieve anoxia quickly,besides,lung protective ventilation is better than traditional mechanical ventilation on the rate of complication and death rat.
出处
《中外医学研究》
2012年第13期24-25,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
