摘要
目的:对急性呼吸窘迫综合征患者应用机械通气治疗的效果进行分析探讨。方法:选取2013年5月-2014年10月在笔者所在医院进行治疗的46例急性呼吸窘迫综合征患者作为研究对象,按照随机数字表法将其分为观察组和对照组,每组23例。对照组患者应用传统的机械通气法治疗,观察组患者应用肺保护性机械通气法治疗。观察两组患者治疗前后的Pa O2和Pa CO2,对待机时间、VAP发生情况和病死情况进行比较。结果:治疗后,两组患者的Pa O2和Pa CO2均较治疗前明显改善,差异均有统计学意义(P<0.05),但两组间比较差异均无统计学意义(P>0.05)。观察组患者的待机时间明显短于对照组,VAP发生率13.0%和病死率17.4%均明显低于对照组的43.5%和47.8%,比较差异均有统计学意义(P<0.05)。结论:急性呼吸窘迫综合征患者应用肺保护性机械通气治疗能够有效缓解其缺氧状态,同时具有较低的VAP发生率和病死率,具有重要的临床应用价值。
Objective： To investigate and analyze the application effect of mechanical ventilation in the treatment of acute respiratory distress syndrome patients.Method： 46 cases of patients with acute respiratory distress syndrome in our hospital from May 2013 to October 2014 were selected as research objects, they were divided into the observation group and the control group according to the random number table method, 23 cases in each group.The control group was treated with traditional mechanical ventilation, the observation group was treated with lung protective mechanical ventilation.The PaO2 and PaCO2 before and after the treatment, standby time, VAP occurrence and case fatality of the two groups were observed and compared.Result： After the treatment, the PaO2 and PaCO2 of the two groups were significantly improved, the differences were statistically significant（P〈0.05）, but there were no significant differences between the two groups（P〉0.05）.The standby time of the observation group was significantly shorter than that of the control group, the incidence of VAP and case fatality rate of the observation group were 13.0% and 17.4%, which were significantly lower than 43.5% and 47.8% of the control group, the differences were statistically signifieant（P〈0.05）.Conclusion： The treatment of acute respiratory distress syndrome patients with lung protective mechanical ventilation can effectively alleviate the hypoxia, while having lower VAP incidence and mortality rate, and it has important clinical application value.
出处
《中外医学研究》
2015年第17期4-5,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
急性呼吸窘迫综合征
机械通气
临床效果
Acute respiratory distress syndrome
Mechanical ventilation
Clinical effect
