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血清视黄醇结合蛋白4水平与脑梗死及其危险因素的相关性 被引量:3

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摘要 目的探讨血清视黄醇结合蛋白4(RBP4)与脑梗死及其危险因素之间是否具有相关性。方法从该院脑梗死注册系统中选取2008年1月至2010年7月间住院的200例脑梗死患者为观察组。按入院时RBP4水平将观察组分为RBP4正常组89例,RBP4增高组111例,以同期体检健康者76例为对照组。比较观察组与对照组血清RBP4水平,及两个亚组间脑梗死危险因素(高血压、糖尿病、心脏病、肥胖、吸烟、饮酒、颈动脉狭窄)的检出率。分析RBP4与脑梗死各个危险因素的相关性。结果与对照组比较,观察组RBP4水平明显增高(P<0.01)。与对照组和RBP4正常亚组相比较,RBP4增高亚组在颈动脉狭窄、糖尿病、肥胖、吸烟等危险因素中有较高检出率(P<0.05)。Logistic回归分析并校正性别、年龄影响,RBP4与脑梗死危险因素中的颈动脉狭窄、吸烟、肥胖独立相关。结论 RBP4可能在脑梗死的发生中起一定的作用,且与颈动脉狭窄、肥胖、吸烟等因素呈正相关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第6期1136-1137,共2页 Chinese Journal of Gerontology
基金 武汉市卫生局基金资助项目(WX11D15)
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