摘要
[目的]研究制备芒果苷磷脂复合物的最佳制备工艺。[方法]以芒果苷与磷脂的复合率为评价标准,采用单因素考察和正交实验筛选工艺参数。[结果]确定了制备芒果苷磷脂复合物的最佳工艺条件:以甲醇-丙酮为反应溶剂,芒果苷质量浓度为0.25 g/L,物料比摩尔比为1∶1,反应温度为40℃,反应时间为2 h。[结论]优化工艺可制得复合率较高的芒果苷磷脂复合物,简单可行。
[Objective] To determine the best technology for preparing Mangiferin phospholipids complex.[Methods] The compounding rate of mangiferin and phospholipid was investigated with mono-agent investigation and orthogonal design test to analyze the technological parameters.[Results] The best conditions for preparing mangiferin phospholipid complex were as follows： methanol and acetone were used as reaction solvent,concentration of mangiferin in solvent was 0.25 g/L,molar ratio of mangiferin and phospholipid was 1∶1,react was performed for 2.0 hr at 40 ℃.[Conclusion] The optimized preparing technology can get mangiferin phospholipid complex with a high compounding rate.The technology is easy and feasible.
出处
《天津中医药》
CAS
2012年第1期83-85,共3页
Tianjin Journal of Traditional Chinese Medicine
基金
天津市高等学校科技发展基金计划项目(20100211)
关键词
芒果苷
磷脂复合物
制备工艺
mangiferin
phospholipid complex
preparation method
