摘要
目的探讨半夏厚朴汤合并西酞普兰对产后抑郁症患者的疗效。方法将192例产后抑郁症患者随机分成研究组(用半夏厚朴汤合并西酞普兰系统治疗)和对照组(单用西酞普兰系统治疗),共治疗4周,采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、副反应量表(TESS)评定疗效和副反应。结果在第1周末,研究组的HAMD和HAMA评分与治疗前比较均降低(P<0.05)。在第2、4周末,两组的HAMD和HAMA评分与治疗前比较均有显著性降低(P<0.01)。在治疗后第1、2、4周末,HAMD和HAMA评分两组间比较差异均有显著性意义(P<0.01)。两组不良反应均较少。结论半夏厚朴汤合并西酞普兰可有效、快速治疗产后抑郁症患者的抑郁及焦虑症状,疗效优于单用西酞普兰。
Objective To explore the efficacy and safety of Banxia Houpu Tang combined with citalopram in treatment of patients with postpartum depression. Methods A total of 192 patients with postpartum depression were randomly divided into study group with Banxia Houpu Tang combined with citalopram and control group with citalopram for 4 weeks of treatment. They were assessed and analyzed contrastively using Hamilton Depression Scale （HAMD） , Hamilton Anxiety Scale （HAMA） for clinical efficacy and Treatment Emergent Symptom Scale （TESS） for side effects. Results At the end of 1 st week, the scores of HAMD and HAMA in study group were significantly lower than those before treatment（P 〈0.05）. At the end of 2nd and 4th week, the scores of HAMD and HAMA in two groups were significantly lower than those before treatment（P 〈0.05）. At the end of 1st, 2nd and 4th week, the scores of HAMD and HAMA in study groups were all significantly lower than those in control group （P 〈 0.05 ）. There were no severe side effects in study group and control group. Conclusion Banxia Houpu Tang combined with citalopram should be effective and rapid in treatment of patients with postpartum depression which is better than citalopram.
出处
《精神医学杂志》
2012年第1期45-47,共3页
Journal of Psychiatry
关键词
半夏厚朴汤
西酞普兰
产后抑郁症
Banxia Houpu Tang Citalopram Postpartum depression
