摘要
作为心境障碍常见疾病的抑郁症,已成为全球四大致残疾病之一。目前,抑郁症受到众多研究者的关注,其昼夜节律紊乱也是许多精神疾病的主要危险因素之一。昼夜节律紊乱的生物时钟可致抑郁症的病情加重或复发。因此,调节昼夜节律的恢复,已逐步成为抑郁症治疗的有效标志。当前调节昼夜节律的临床用药治疗有限。所以探索调节昼夜节律诊疗,对于预防及治疗抑郁症具有重要意义。中医认为情志性的昼夜节律紊乱与肝脏密切相关,探讨肝与昼夜节律的生理病理,总结疏肝法治疗昼夜节律紊乱的关键性及临床应用研究。创新性提出中医"疏肝调律法"可能为预防和治疗抑郁症昼夜节律紊乱的临床诊疗开辟新思路、新途径。
Depression,a common disorder of mood disorders,has become one of the four major disabling diseases in the world.At present,research on depression has attracted the attention of many researchers,and its circadian rhythm disorder is also one of the main risk factors for many mental diseases.The circadian rhythm of the biological clock can cause depression to worsen or relapse.Therefore,regulating the recovery of circadian rhythm has gradually become an effective sign of depression treatment.The current clinical medications for regulating circadian rhythm are limited.Therefore,exploring and adjusting the circadian rhythm diagnosis and treatment is of great significance for the prevention and treatment of depression.Traditional Chinese medicine believes that emotional circadian rhythm disorders are closely related to the liver.The physiology and pathology of the liver and circadian rhythms are explored,and the method of soothing the liver is the key to the treatment of circadian rhythm disorders and clinical application research.Innovatively proposing the“soothing liver and regulating rhythm”of traditional Chinese medicine may open up new ideas and new ways for the prevention and treatment of circadian rhythm disorders in depression.
作者
张瑞环
何旭
姚震
陈钧
ZHANG Ruihuan;HE Xu;YAO Zhen;CHEN Jun(Shaanxi University of Traditional Chinese Medicine,Xianyang 712046,Shaanxi,China;Shaanxi Provincial of Traditional Chinese Medicine,Xi'an 710000,Shaanxi,China)
出处
《辽宁中医药大学学报》
CAS
2021年第12期203-207,共5页
Journal of Liaoning University of Traditional Chinese Medicine
基金
陕西省人才推进计划(2017KJXX-84)
陕西省“特支计划”项目
关键词
抑郁症
昼夜节律
天人感应
疏肝调律
depression
circadian rhythm
interaction between heaven and mankind
soothing regulate liver and regulating rhythm
