摘要
应用放射免疫法，对产后抑郁症患者２０例（抑郁症组）及未患产后抑郁症妇女２０例（对照组），于妊娠３６～３７周、产后４８小时测定血清β－ｈＣＧ、孕酮（Ｐ）及雌二醇（Ｅ＿２）。结果：抑郁症组产前β－ｈＣＧ、Ｐ浓度及产前产后浓度差值均高于对照组，差异有显著性，尤其Ｐ浓度，产后明显下降；产后两组激素水平接近，差异均无显著性；两组Ｅ＿２水平，无论产前、产后及产前产后浓度差值均接近，差异无显著性。提示：在胎盘娩出后，β－ｈＣＧ及Ｐ明显下降，可能对产后抑郁症的发生有影响。
renatal and postpartum measurements of serum β-hCG, estradiol(E_2)and progesterone(P)con-centration were done by radioimmunoassay in 20 cases of postpartum depression(PD)and 20 cases with-out postpartum depression(NPD).The results showed significantly higher serum levels of P and β-hCG(at 36～37 gestational week) in PD, but no difference in the serum P and β-hCG concentration between the PD and NPD after childbirth.The falling of the two hormones was faster in PD than in NPD. In neither prenatal nor postpartum test was any difference seen in serum E2 concentration between PD and NPD. These results suggest that supposely,the endogenous risk factor,the rapid withdrawal of the pla-cental hormones(P and β-hCG)after delivery,leads to PD.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1995年第6期342-344,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
抑郁症
孕酮激素
雌二醇
HCG
产褥期
Depression Progestational Estradiol Gonadotropins, chorionic Puer-perium
