摘要
目的探讨急性白血病(非M3)住院患者医院感染的临床特点及风险因素分析。方法选取急性白血病(非M3)患者186例,其中88例共发生107例次医院感染。采用回顾性分析的方法,对临床资料完整的88例急性白血病(非M3)医院感染患者的感染部位、病原体、住院时间及感染的危险因素进行分析。结果感染部位:上呼吸道感染例次较多(34.58%),其次为下呼吸道感染(26.17%);上呼吸道感染住院时间最短,泌尿道感染住院时间最长;病原菌构成:107例次感染中,共分离出86株病原菌,其中革兰阳性菌30株,革兰阴性菌49株,真菌7株;患者年龄>60岁,中性粒细胞数<1.0×109/L和疾病处于非缓解状态为急性白血病发生医院感染的危险因素。结论急性白血病患者发生医院感染率较高,应降低急性白血病患者体内外易感因素,减少医院感染的发生,以期提高治疗效果。
Objective To explore the clinical feature and risk factors of acute leukemia patients（non-M3 subtype）with hospital infection.Methods 186 patients of acute leukemia（non-M3 subtype） were selected.88 patients（107 cases） with hospital infection were found.Site infection,pathogen,hospital stays and risk factors were analyzed.Results Site infection： upper respiratory infection was 34.58% and lower respiratory tract infection was 26.17%.The hospital stays of upper respiratory infection was shortest,and urinary tract infection was longest.Pathogen constitute：86 strains pathogen were separated 30 strains included Gram-positive bacteria,49 strains Gram-negative bacteria and 7 strains fungi.The patients with age60 years,ANC1.0×109/L and non-remission were the risk factors.Conclusion The hospital infection rate of acute leukemia patients is high,clinician should eliminate risk factors in vivo and vitro,reduce the hospital infection for better therapeutic efficacy.
出处
《湖南中医药大学学报》
CAS
2012年第2期58-59,71,共3页
Journal of Hunan University of Chinese Medicine
关键词
急性白血病
医院感染
临床特点
危险因素
Acute leukemia
Hospital infection
Clinical feature
Risk factors
