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检测胃癌血清和腹水中CA72-4抗原水平的临床意义 被引量:2

Clinical significance of CA72-4 antigen levels In serum and peritoneal washing for gastric carcinoma
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摘要 目的:对胃癌患者进行CA72-4含量的检测,分析血清和腹水中的CA72-4水平与胃癌的相关性,预期判定腹膜复发的可能性。方法:研究了48例胃癌患者血清和腹水中的CA72-4水平、损伤部位及根除和淋巴结转移的数量。结果:淋巴结转移的胃癌患者与血清和腹水中的高水平CA72-4含量显著相关。浆膜浸润胃癌与血清中的CA72-4水平含量无显著统计学相关性,然而,与腹水中的CA72-4水平含量显著相关。尽管血清中的CA72-4水平含量与晚期胃癌无显著相关性,但腹水中的CA72-4水平含量与晚期胃癌呈显著相关。结论:腹水中的CA72-4高水平含量与淋巴结转移和浆膜浸润胃癌显著相关。血清中的CA72-4水平含量仅与淋巴结转移相关,与浆膜浸润胃癌无显著相关。 Objective To detect the content of CA72-4 antigen in ascites of gastric carcinoma patients, CA72-4 levels in serum and aseitic fluid were detected, the relationship between gastric cancer and CA72-4 levels was determined, the possibility of of recurrence in peritoneum was evaluated. Method CA72-4 levels in serum and ascites in 48 cases with gastric cancer were detected, injury site and the number of eradicated metastatic lymph node were documented. Result High content of CA72-4 in serum and aseites of patients was associated with lymph node metastasis of gastric cancer. No significance statistically was found between serum CA72-4 level and serosal invasion of gastric cancer, however, the level of CA72-4 in ascites was associated with serosal invasion of gastric cancer. Although serum CA72-4 level in serum was not correlated with advanced gastric cancer, CA72-4 level of in ascites of patients was not correlated with advanced gastric cancer. Conclusions CA72-4 high level in aseites were correlated with serosal invasion and lymph node metastasis of gastric cancer. Serum CA72-4 level was only associated with lymph node metastasis, but was not associated with serosal invasion of gastric cancer.
出处 《实用医学杂志》 CAS 北大核心 2012年第3期480-482,共3页 The Journal of Practical Medicine
关键词 胃肿瘤 肿瘤标志物 CA72-4 Gastric tumour Tumor marker CA72-4
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  • 1张青松,胡永奇,周宝臣,钟烁.胃癌术中腹腔灌洗液CA19-9测定的临床意义[J].中国综合临床,2005,21(5):444-445. 被引量:2
  • 2王夫景,高岩,黄跃南,佟佰峰,张秀云,杨维良.腹腔冲洗液和腹膜组织检测胃癌腹腔微转移的临床意义[J].世界华人消化杂志,2005,13(17):2148-2150. 被引量:5
  • 3SHIMADA H, NOIE T, OHASHI M, et al. Clinical significance of sexton tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association [J]. Gastric Cancer, 2014, 17( 1 ) :26-33. 被引量:1
  • 4WU D, GUO Z, LIU Y, et al. Sandwich-type electrochemical using dumbbell-like nanoparticles for the determination of gastric cancer biomarker CA72-4 [J ]. Talanta, 2015,134 : 305-309. 被引量:1
  • 5MATI'AR R, CR ADA, DIFAVERO GM, et al. Preoperative serum levels of ca 72-4, cea, ca 19-9, and Alpha-fetoprotein in patients with gastric cancer [J]. Revista Do Hospital Das Clinicas, 2002,57(3) : 89-92. 被引量:1
  • 6WONG R, TSE H. Lateral flow immunoassay [ J ]. Moscow University Chemistry Bulletin, 2011,67 (6) : 249-253. 被引量:1
  • 7WANG C, HOU F, MAY. Simultaneous quantitative detection of multiple tumor markers with a rapid and sensitive multicolor quantum dots based immunochromatagraphic test strip [J]. Biosensors & Bioelectronies, 2015,68 : 156-162. 被引量:1
  • 8XIAO L, LI J, BROUGHAM DF, et al. Water-soluble superparamagnetic magnetite nanopartieles with biocompatible coating for enhanced magnetic resonance imaging [J]. ACS Nano, 2011,5(8):6315-6324. 被引量:1
  • 9REN M, XU H, HUANG X, et al. Immunochromatographic assay for ultrasensitive detection of aftatoxin B-1 in maize by highly luminescent quantum dot beads [J]. Acs Appl Mater Interfaces, 2014,6( 16): 14215-14222. 被引量:1
  • 10WANG Y, XU H, WEI M, et al. Study of superparamagnetic nanoparticles as labels in the quantitative lateral flow immunoassay [J]. Mater Sci Eng: C, 2009, 29(3) :714-718. 被引量:1

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