摘要
目的探讨原发性渗出性淋巴瘤(PEL)的临床、组织学特点。方法运用细胞形态学、免疫组化及流式细胞技术(FCM)方法研究1例经临床与病理确诊的PEL患者并结合文献进行讨论。结果该病的临床特点是有体腔积液如腹水、胸腔积液和心包积液,但没有可检测到的肿块样病灶,浆膜渗出液中含高度恶性的淋巴细胞。此病多见于HIV感染的患者,也可发生于HIV血清学阴性的患者。结论进一步对本病的病理特征,临床特点加深了解,对提高本病的鉴别诊断、治疗大有裨益。
Objective To explore the clinical and histologic features of primary effusion lymphoma(PEL).Methods 1 case of PEL diagnosed by clinic and pathology was discussed with cytomorphology,immunohistochemical and flow cytometry(FCM) combined with the related literature review.Results The disease was characterized by body cavity-based effusions containing malignant lymphocytes without detectable lump.PEL was usually found in the patients infected by HIV,also occurred to the patient with serological negative HIV.Conclusion Further deepening understanding on the pathological and clinical characteristics of PEL is useful for differentiation diagnosis and treatment of PEL.
出处
《检验医学与临床》
CAS
2012年第2期133-134,137,共3页
Laboratory Medicine and Clinic
基金
上海市宝山区科技项目资助课题(10-e-12)