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微小染色体维持蛋白2在妇科恶性肿瘤研究中的进展 被引量：2

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摘要 微小染色体维持蛋白2(MCM2)是真核细胞DNA复制启动的许可因子。MCM2只在增殖细胞周期中表达,被视为特异性增殖相关因子,能够检测具有增生潜能的细胞和较好地区分正常组织、不典型增生及肿瘤组织。用MCM2作为肿瘤标志物提高了妇科恶性肿瘤的筛查检出率,有助于判定肿瘤预后,MCM2抗体及抑制剂有望成为治疗妇科恶性肿瘤的新靶点。
作者 郑健 任杰 宋静慧
机构地区 内蒙古医学院附属医院妇产科
出处 《现代妇产科进展》 CSCD 北大核心 2011年第12期993-995,共3页 Progress in Obstetrics and Gynecology
基金 内蒙古自治区医疗卫生科研计划项目(No:2010028)
关键词 微小染色体维持蛋白2 妇科恶性肿瘤 综述文献
分类号 R737.33 [医药卫生—肿瘤]
  • 相关文献

参考文献20

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二级参考文献30

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共引文献17

同被引文献25

  • 1王静,马金龙,王家耀,王强修.MCM蛋白与肿瘤[J].医学与哲学（B）,2007,28(3):41-42. 被引量：4
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  • 10刘坚,王郡甫.多肿瘤标志物联合检测在妇科恶性肿瘤临床治疗中的应用研究[J].实用癌症杂志,2008,23(5):480-482. 被引量：3

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现代妇产科进展
2011年 第12期

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