摘要
目的为了评价饮用水源水中有机污染物健康风险及遗传毒性。方法 Z省对水源中176种有机物例行监测,监测结果采用美国国家环保局(US EPA)推荐水环境健康风险评价模型对水源水中有机物经饮水途径导致的健康风险进行评价。结果显示微囊藻毒素(Microcystin,MCs)和草甘膦农药分布广、检出率高,是水中典型的有机污染物。饮用水源中有机物引起的健康风险相对较小,远低于国际权威机构推荐的可接受水平。同时,利用单细胞凝胶电泳法进行DNA损伤分析结果表明,水源水中MCLR、MCRR均可以造成淋巴细胞DNA链明显损伤,草甘膦也可导致人外周血淋巴细胞DNA不同程度的损伤,而且DNA损伤效应可能受到水源水中其他组分的影响。结论显示了水中有机物遗传毒性作用的复杂性。
Objectives To assesse the health risk and genotoxicity of organic pollutans in source waters. Methods A total of 176 kinds of organic pollutants in source waters in Z province were investigated. The health risk of organic pollutants had been assessed by means of the model recommended by US EPA. Results It is showed that Microcystins （MCs） and Glyphosate were the typical pollutants distributed wildy in the source waters of Z proveince and the concentrations of them were much higher than other pollutants. The results also displayed that the health risk of organic pollutants in source waters was much lower than the acceptable limits recommended by international authorities. Meanwhile, single cell gel electrophoresis （SCGE） was used to test DNA damage and the results declared that MCLR or MCRR in source waters all resulted in DNA damage of lymphocytes significantly, and Glyphosate also induced DNA damage of peripheral lymphocytes in different levels, which was affected by other components in source waters. Conclusion The results indicated that the genetoxic effects were complicated in soure waters.
出处
《环境卫生学杂志》
北大核心
2011年第1期4-10,24,共8页
JOURNAL OF ENVIRONMENTAL HYGIENE
