摘要
目的探讨左氧氟沙星治疗合并慢性乙型肝炎的肺结核患者临床疗效及安全性。方法 77例处于非活动期或肝功能轻度异常的慢性乙型肝炎合并肺结核患者,随机分为治疗组38例予以3HREV/6HRE治疗,对照组39例予以3HREZ/6HRE治疗。结果治疗组肝功能损害发生或者加重几率23.7%,对照组肝功能损害发生或者加重几率48.7%,两组差异有显著性(P<0.05)。治疗组抗结核总有效率92.1%,对照组总有效率94.9%,抗结核化疗总有效率无显著性差异(P>0.05)。结论左氧氟沙星治疗慢性乙型肝炎合并肺结核患者临床疗效好,且肝毒性小,值得临床推广应用。
Objective To observe the effect of levofloxacin on pulmonery tuberculosis patients with chronic hepatitis B.Methods 77 pulmonery tuberculosis patients with chronic hepatitis B were randomly divided into two groups.Treatment group was treated with 3HREV/6HRE and control group with 3HREZ/6HRE.Results The liver injury rate of treatment group and control group were 23.7% and 48.7%,respectively（P〈0.05）.The total effective rate of treatment group and control group were 92.1% and 94.9%（P〉0.05）.Conclusion It was effective to treat pulmonery tuberculosis with levofloxacin.
出处
《西部医学》
2011年第11期2166-2167,共2页
Medical Journal of West China
关键词
左氧氟沙星
慢性乙型肝炎
肺结核
Levofloxacin
Chronic hepatitis B
Pulmonery tuberculosis
