摘要
目的乙型肝炎合并肺结核的患者在抗结核化疗过程中,辅以抗病毒、护肝治疗的效果观察。方法将乙型肝炎合并肺结核患者56例,随机分为2组:抗结核+抗病毒治疗+护肝治疗组(A组);抗结核+护肝治疗组(B组),观察肝功能情况。结果 B组ALT、AST和T-BIL、HBV-DNA高于A组,两者差异显著(P<0.05);B组肝功能异常率高于A组,两者差异显著(P<0.05);B组停药率高于A组,两者差异显著(P<0.05)。结论抗病毒治疗能明显减轻乙型肝炎合并肺结核的患者抗结核治疗引起的肝功能损害,减少抗结核治疗的停药率。
Objective To study whether a TB patient with hepatitis B treated by antituberculotic should be hospitalized for the observation in order to achieve antibiral and protection of liver at the same time.Methods 56 TB patients with hepatitis B were divided into two groups and their damage of liver function were observed.Group A： lariatin＋antivirus＋protection of liver;Group B：lariatin＋protection of liver.Results The observational measures of ALT,AST,T-BIL and HBV-DNA in was higher in Group B than those in Group A,and the difference of these two has statistical significance（P0.05）.The abnormal rate of the liver function in Group B was also higher than that in Group A,and the difference of these two has statistical significance（P0.05）.And the rate of the drug withdrawal in Group B was again higher than that in Group A,and the difference of these two has statistical significance（P0.05）.Conclusions The antivirus treatment can not only reduce the damage of liver function cased by anti-TB treatments,but also reduce the rate of the drug withdrawal.
出处
《临床肺科杂志》
2011年第12期1896-1898,共3页
Journal of Clinical Pulmonary Medicine
