摘要
目的:对艾滋病中医证候规律进行研究,探讨艾滋病发病机制,为临床和实验研究提供依据。方法:检索相关文献,以证为中心对文献进行提取。建立Excel数据表,并对提取数据进行统计分析。结果:艾滋病所涉及的证型、证素和症状数据显示艾滋病临床证候以虚证为多,分布较为分散;病位集中在脾、肺、肾、胃、心、肌肤和肝等脏腑;病性集中在气虚、火(热)、湿、阴虚、毒、痰、血瘀、阳虚等方面;艾滋病常见症状为发热、神疲乏力、腹泻、脉细、消瘦、食欲减退等30项。Logistic回归分析结果进一步揭示了艾滋病证候所涉及的证素和证候之间存在的内在联系。结论:艾滋病文献中证候的规律和特点反映了其本虚标实、阴阳失调、虚实夹杂的基本病机,提示艾滋病发病具有正气亏虚、邪毒入侵、脏腑受损、瘀血阻络、湿热内蕴等病理机制。
Objective： To study the TCM syndrome law of AIDS and evaluate the pathogenesis of AIDS,thus providing evidence for the clinical and experimental research.Methods： To search related literature for the extraction of the literature with syndrome as the outline.Create Excel data tables,and extract data for statistical analysis.Results： The syndromes,syndrome elements and symptom data involved by AIDS showed that the clinical syndrome of AIDS was mainly deficiency syndrome with dispersed distribution;disease location was concentrated in Spleen,Lung,Kidney,Stomach,heart,skin and liver,et al;pathogenesis was concentrated in Qi deficiency,fire（heat） pathogen,dampness pathogen,Yin deficiency,toxins,phlegm,blood stasis,Yang deficiency,et al;there are 30 common symptoms of AIDS,such as fever,fatigue,diarrhea,emaciation,anorexia,et al;internal relations between syndrome elements and syndromes of AIDS was proclaimed by Logistic analysis.Conclusion： The law and characteristics of AIDS syndromes reflect that the basic pathogenesis is asthenia in origin and excess in superficiality,imbalance of Yin and Yang and deficiency syndrome mingling with excess syndrome,suggesting that the onset of AIDS has the pathological mechanism of healthy-qi deficiency,impairment of zang and fu organs,blood stasis and obstruction of damp-heat inside.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2011年第11期2513-2516,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家973计划(No.2006CB504802)
国家“十一五”科技攻关项目(No.2009ZX10005-02)
国家自然科学基金项目(No.90409004)~~
