摘要
目的探讨湖北省家庭内多人感染HIV的原因,为制定控制HIV家庭内传播策略提供依据。方法收集至2009年底全省有2人及以上感染HIV家庭的艾滋病病毒感染者和艾滋病病人的有关情况,进行统计分析。结果(1)全省有2人及以上患有HIV的家庭比例为16.50%,发生家庭内二代传播的家庭比例为12.31%;(2)家庭内不同的首次感染HIV方式对家庭内发生二代传播的时间间隔有影响,首次经性感染后再经性的二代传播速度明显快于首次经血感染的(t=4.247,P<0.01)和母婴传播(t=2.908,P<0.01)的方式;(3)男女配偶间HIV传播效率男性要高于女性(χ2=9.121,P<0.01);(4)家庭内首发感染者性别、年龄、文化程度对是否发生家庭二代传播没有影响(χ2=0.641或F=2.836或χ2=4.174,P均>0.05),但开展艾滋病抗逆转录病毒治疗、感染者不到外地打工或是经商可以明显减少家庭内HIV二代传播的发生(χ2=294.970或χ2=31.687,P均<0.05)。结论首次经性感染后再发生家庭内经性二代传播的传播速度明显快于首次经血感染和母婴传播的方式;男女配偶间HIV传播效率男性要高于女性;及早开展抗逆转录病毒治疗、减少感染者外出打工或经商均可有效控制家庭内HIV的二代传播。
Objective To study the cause of multiple HIV infection within a family in the central province,and provide basis of formulating the strategies for controlling HIV within a family.Methods Statistical analysis of the data relating two or more infected persons and AIDS patients within a family in Hubei by the end of 2009 were performed.Results The results showed that the rate of two or more people infected with HIV in the whole province was 16.5%,and the rate of the second-generation transmission within the family was 12.31%.Meanwhile,the different way of the first HIV-infection in the family had influence on the interval of the second-generation inflection.The infection speed through first sex-contact and second-generation-sex transmission was obviously faster than that of the first infection through blood（t=4.247,P0.01）） and mother-to-child transmission（t=2.908,P0.01）;the spread by men are higher than that of women within a family（χ2=9.121,P0.01）;The sex,age and education background of the first infected person had no influence on the second-generation transmission within family（χ2=0.641 or F=2.836 or χ2=4.174,P0.05）.However,the implementation of anti-HIV treatment,the limitation of migrant workers and engaging in business outside,might significantly reduce the second-generation HIV infection within family.（χ2=294.970 or χ2=31.687,P0.05）. Conclusion The infection speed through first sex-contact and second-generation-sex transmission was obviously faster than that of the first infection through blood（t=4.247,P0.01）and mother-to-child transmission（t=2.908,P0.01）;the spread by men was higher than that of women within a family.（χ2=9.121,P0.01）.The implementation of anti-HIV treatment,the limitation of migrant workers and engaging in business trip,might effectively control the spread of HIV transmission of the second generation.
出处
《公共卫生与预防医学》
2011年第5期14-17,共4页
Journal of Public Health and Preventive Medicine
关键词
艾滋病
家庭传播
AIDS
Transmission within the family
