摘要
目的探讨河南地区家庭内夫妻间艾滋病病毒（HIV）传播率及其危险因素，为制定防治措施提供科学依据。方法以夫妻一方是HIV阳性，通过性行为导致对方感染HIV的作为病例，对方未被感染的夫妻为对照，探讨影响性传播的危险因素。结果发生HIV性传播的夫妻占全部有性传播危险夫妻的11．99％。单因素分析结果显示：性别（男传女／女传男：OR=2．41，95％C11．31～4．43）、年龄（43岁）（OR=1．96，95％CI 1．06～3．62）、不使用安全套（OR=5．32，95％CI 2．29～11．75）、CD4细胞数〈200个/μl（OR=2．70，95％CI 1．12～6．67）、月性生活频率≥4次（OR：9．49，95％C13．94～22．82），是引起夫妻间传播的危险因素。（2）Logistic回归分析结果显示：不使用安全套（OR：3．82，95％CI 1．32～10．99）和男性配偶阳性（OR=2．46，95％CI 1．30～4．67），是影响夫妻间HIV传播的独立危险因素。结论河南部分地区有稳定婚姻关系的夫妻中HIV传播率为11．99％，配偶中先感染一方为男性和不使用安全套是夫妻间HIV传播的独立危险因素。
Objective To provide scientific evidence for the prevention and control of HIV/AIDS by investigating HIV transmission rate between spouses and related risk factors. Methods The spouses of whom one was infected with HIV by him or her through sexual contact were selected as the case group, while those without infection were selected as the control group. The risk factors for the transmission between husbands and wives were evaluated. Results The couples infected with HIV via sex between them accounted for 11.99 % of all the couples who were at risk of sexual transmission. The results of the univariate analysis showed that the risk factors that might influence the transmission between the spouses included gender disparity（HIV transmission occurred from husband to wives or vice verse）（OR = 2.41,95 % CI 1.31 -4.43） ,age（40 years as a risky age） （OR= 1.96,95%CI 1.06 3.62） ,condom use（OR= 5.32,95%CI 2.29 - 11.75） ,CD4 level（OR=2.70,95% CI 1.12 6.67） ,and frequencies of sexual intercourses（≥4 times per month） （OR = 9.49,95 % CI 3.94 - 22.82）. The results of the Logistic regression analysis indicated that gender disparity（OR = 2.46, 95%CI 1.30 4.67）and non-condom use（OR=3.82,95%CI 1.32- 10.99）were the most important risk factors for HIV transmission between spouses. Conclusions The transmission probability between spouses is 11.99 %. The independent risk factors for sexual transmission between spouses were HIV positive husbands who transmit infections to their wives and non-condom use.
出处
《中国艾滋病性病》
CAS
2008年第1期39-41,共3页
Chinese Journal of Aids & STD
关键词
艾滋病
性传播
危险因素
HIV/AIDS
Transmission between spouses
Risk factor
