摘要
目的:研究巴戟天中主要环烯醚萜苷-水晶兰苷和去乙酰基车叶草苷酸的稳定性和转换条件。方法:利用HPLC,测定不同年份生巴戟天中水晶兰苷和去乙酰基车叶草苷酸的含量,以探寻二者在植物体自身环境内的稳定性;观察水晶兰苷和去乙酰基车叶草苷酸在不同pH(人工胃液、水、人工肠液)下的转化情况,以探寻二者在不同pH溶液中的稳定性。结果:水晶兰苷和去乙酰基车叶草苷酸在巴戟天中的含量相对稳定,前者在人工胃液中可以转化为后者。结论:水晶兰苷和去乙酰基车叶草苷酸在巴戟天中相对稳定;水晶兰苷在酸性条件下不稳定,可以转化为结构比较稳定的去乙酰基车叶草苷酸。
Objective：To study stability and transformation of monotropein and deacetylaspcrulosidic acid,which were the main iridoid glucosides from Morindae Officinalis Radix.Method： The content of monotropein and deacetylaspcrulosidic acid from different years of Morindae Officinalis Radix were determined by HPLC to find out the stability in plants.The conversion of monotropein and deacetylaspcrulosidic acid in artificial gastric,water and artificial intestinal juice was studied to seek the stability in different pH solution.Result： The content ratio of monotropein and deacetylaspcrulosidic acid from different years of Morindae Officinalis Radix maintain similar.Monotropein converted to deacetylaspcrulosidic acid in artificial gastric.Conclution： The contents of monotropein and deacetylaspcrulosidic acid is relatively stable in Morindae Officinalis Radix.Monotropein can converted to deacetylaspcrulosidic acid in acidic condition.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第21期65-68,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81072801)
北京市自然科学基金项目(7093129)
