摘要
目的了解我院药品不良反应(ADR)发生的特点及规律。方法对我院2009年4月至2010年5月收集的107例ADR报告,按患者性别、年龄、给药途径、药物剂型、药品种类、ADR累及器官或系统及临床表现等进行分类统计与分析。结果 107例报告中,涉及药品69种;以抗感染药居多,占48.62%;静脉给药方式是引发ADR的重要给药途径,占81.31%;ADR最常见的临床表现为皮肤及其附件损害,占35.53%。结论临床应进行必要的用药干预和指导,加强ADR监测,以减少ADR的发生率。
Objective To investigate the characteristics and general pattern of drug adverse reactions （ADR） occurred in ourhospital. Methods A total of 107 ADR cases reported in our hospital from Apr. 2009 to Mar. 2010 were analyzed statistically in respect of patients＇age and sex, route of administration, dosage form, category of drug, organs and systems involved in ADR and clinical manifestions etc. Results 69 kind of drug were involved in 107 ADR cases, 48.6% were induced by anti - infective drugs, 81.31% were induced by means of intravenous route, and 35.53% manifested as lesions of skin and its appendants. Conclusion It was necessary to intervene and guide clinical use of drug, strengthen monitoring of ADR and reduce occurrences of ADR.
出处
《药学实践杂志》
CAS
2011年第5期394-395,397,共3页
Journal of Pharmaceutical Practice
关键词
药品不良反应
报告
分析
adverse drug reactions （ADR）
reports
analysis
