摘要
目的:评价五脏俞加膈俞为主辨证治疗原发性抑郁症的疗效。方法:将60例原发性抑郁症患者随机分为针刺组(31例)和西药组(29例),针刺组以五脏俞加膈俞辨证加减,肝郁脾虚者配太冲、三阴交,心脾两虚者配神门、三阴交;西药组口服盐酸氟西汀胶囊20mg,每日1次,均治疗6周。治疗2、4、6周后分别对汉密尔顿抑郁(HAMD)量表、HAMD因子分析、Asberg副作用量表进行评分,对比两组临床疗效。结果:治疗6周后,针刺组总有效率为67.7%(21/31),西药组为65.5%(19/29),两组疗效相近(P>0.05)。两组治疗2、4、6周后HAMD评分、焦虑躯体化因子、睡眠因子、迟缓因子评分均较治疗前明显下降(均P<0.01);两组组间治疗后各时间点比较,针刺组焦虑躯体化因子、睡眠因子较西药组改善明显(均P<0.05),西药组迟缓因子较针刺组改善明显(P<0.05)。西药组Asberg量表评分在2周时达到高峰,之后呈缓慢下降趋势,针刺组副作用趋势低平,治疗6周后比较总体低于西药组(P<0.05)。结论:辨证治疗抑郁症的针灸经验方与口服盐酸氟西汀胶囊近期疗效相当,副作用较盐酸氟西汀胶囊少。
Objective To evaluate the curative effect of primary depression treated with the main points of Back-shu points of Five-zang and Geshu （BL 17） according to the differentiation. Methods Sixty cases of primary depression were randomly divided into an acupuncture group （31 cases.） and a western medication group （29 cases）. In acupuncture group, Back-shu points of Five-zang and Geshu （BL 17） were applied as the main points, Taichong （LR 3） and Sanyinjiao （SP 6） were added for stagnation of liver qi and spleen deficiency; Shenmen （HT 7） and Sanyinjiao （SP 6） were added for deficiency of both heart and spleen according to the differentiation. In western medication group, Fluoxetine Hydrochloride capsule was taken by oral administration for 20 mg, once a day. The treatment lasted for 6 weeks in both groups. After 2, 4, and 6 weeks treatment, the clinical curative effects of both groups were assessed by Hamilton Depression （HAMD） Rating Scale, HAMD Factor Analysis and Asberg Side Effect Scale. Results After 6 weeks treatment, the total effective rate was 67.7% （21/31） in acu- puncture group and 65.5% （19/29） in western medication group, indicating the close curative effeets（P〉0.05）. After 2, 4, and 6 weeks treatment, the HAMD score, scores of anxious somatization, sleeping and retardation factors were significantly reduced （all P〈0.01） in two groups, through the comparison at different time points between two groups, scores of anxious somatization, sleeping factors in acupuncture group were superior to those in western medication group （both P〈0. 05）, but score of retardation factor in western medication group was superior to that in acupuncture group（P〈0. 05）. The Asberg Side Effect Scale in western medication group arrived at peak at theseeond week, and then reduced slowly; the side effect in acupuncture group was low and steady, and lower than that in western medication group after 6 week treatment（P〈0.05）. Conclusion The curative effect of depr
出处
《中国针灸》
CAS
CSCD
北大核心
2011年第10期875-878,共4页
Chinese Acupuncture & Moxibustion
基金
首都医学发展科研基金项目:SF-2007-Ⅲ-26
关键词
抑郁症
针灸治疗
穴
背俞
穴
膈俞
Depression
Acupuncture Therapy
Points, Back Shu
Point BL 17（Geshu）
