摘要
背景:透析膜的生物相容性与否直接关系到维持性血液透析患者的生活质量与生存率。目的:比较PolyamixTX与F7HPS两种透析膜对尿素氮、肌酐等代谢废物的清除效果。方法:选择2008-06/2011-03天津市海河医院门诊尿毒症维持性常规血液透析患者40例,随机分为F7HPS膜材料和PolyamixTX膜材料组,每组20例。比较透析前后患者尿素氮、肌酐下降程度,观察不同透析膜治疗后低血压、抽搐发生情况。结果与结论:PolyamixTX膜材料组和F7HPS膜材料组透析6个月后尿素氮、肌酐与透析前相比均显著下降(P<0.05),F7HPS膜材料组下降更多。F7HPS膜材料组20例患者中15例并发低血压、抽搐,PolyamixTX膜材料组中7例并发低血压、抽搐,未见其他并发症发生。提示F7HPS具有相对好的溶质清除力,但发生低血压、抽搐等并发症的情况也较多。
BACKGROUND：Whether the biocompatibility of dialysis membrane is directly related to the quality of life and survival of hemodialysis patients is unknown. OBJECTIVE：To compare the effect of PolyamixTX and F7HPS two dialysis membrane for the remove of urea nitrogen and creatinine metabolic waste. METHODS：Forty cases uremia patients undergoing routine maintenance hemodialysis were chosed from the Outpatient of Haihe Hospital of Tianjin from 2008-06 to 2011-03,and then randomly divided into F7HPS membrane group and PolyamixTX membrane group,each group of 20 cases. Urea nitrogen and serum creatinine levels were compared between two groups,and the incidence of hypotension and convulsion was observed after dialysis membrane treatment. RESULTS AND CONCLUSION：The levels of urea nitrogen and serum creatinine were both decreased significantly in the two groups after treatment as compared with those prior to treatment（P 0.05） . F7HPS had relatively good solute remove force,but 15 of 20 patients had hypotension and convulsion. In the PolyamixTX group,only 7 patients appeared with hypotension and convulsion.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2011年第34期6302-6305,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
