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同期放化疗治疗IIb、Ⅲ期宫颈癌60例近期疗效观察 被引量:2

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摘要 【目的】评价同期放疗加化疗治疗中晚期宫颈癌的近期疗效及化疗对放疗副反应的影响。【方法】120例初治中晚期官颈癌随机分为观察组(A组)和对照组(B组),每组60例。A组:放射治疗期间每周采用顺铂(40mg/m^2)化疗1次,共5次。B组仅单纯放疗。两组的放疗均用全盆四野外照,DT46Gy,每周4次,同时Ir腔内放疗A点剂量DT35~42Gy,每次7Gy,每周1次,共5~6次。【结果】所有病人均顺利完成治疗。A组近期完全消退率(83.3%)高于B组(53.3%),差异有统计学意义(P〈O.05)。【结论】采用顺铂为放疗增敏剂同期放化疗可以提高中晚期宫颈癌的肿瘤消退率,无明显毒副反应。
作者 刘晓华 郑江
出处 《医学临床研究》 CAS 2011年第8期1586-1587,共2页 Journal of Clinical Research
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