期刊文献+

早期乳腺癌保乳术加放疗的临床疗效观察 被引量:6

下载PDF
导出
摘要 目的评价早期乳腺癌保乳术后放疗的临床疗效。方法选取1983~2006年在我院行保乳手术且病例资料保存完整的早期乳腺癌患者422例为研究对象,对其临床资料进行回顾分析。结果患者5年生存率97.4%、无瘤生存率93.3%、无局部复发生存率96.6%、无远处转移生存率96.3%,10年生存率85.2%、无瘤生存率78.8%、无局部复发生存率89.7%、无远处转移生存率89%。25例患者出现局部区域复发。单因素分析显示术后放疗、辅助化疗、清扫淋巴结总数是影响局部复发的危险因素。多因素分析显示术后放疗是减少局部复发的惟一影响因素。保乳治疗后患者美容效果评价佳者达90.3%。导管内癌及小叶原位癌患者预后良好。结论早期乳腺癌保乳治疗安全有效。放疗可以降低局部复发率,提高生存率,在保乳术后占据重要地位。
出处 《山东医药》 CAS 北大核心 2011年第32期48-50,共3页 Shandong Medical Journal
  • 相关文献

参考文献7

二级参考文献32

  • 1儿玉宏 金方堂.乳房温存疗法[M].京都:,1998.75-76. 被引量:1
  • 2Recht A. The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast cancer[ J]. N Engl J Med,1996,334(21 ) :1356 - 1361. 被引量:1
  • 3Bedwinek J. Treatment of stage I and Ⅱ adenocarcinoma of the breast by tumor excision and irradiation. Int J Radiat Oncol Biol Phys, 1981,7: 1553-1559. 被引量:1
  • 4Park CC, Mitsumori M, Nixon A, et al. Outcome at 8 years after breast-conserving surgery and radiation therapy for invasive breast cancer: influence of margin status and systemic therapy on local recurrence. J Clin Oncol,2000, 18: 1668-1675. 被引量:1
  • 5Smitt MC, Nowels KW, Zdeblick MJ, et al. The importance of the lumpectomy surgical margin status in long-term results of breast conservation. Cancer, 1995,76:259-267. 被引量:1
  • 6Bartelink H, Horiot JC, Poortmans P, et al. Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med,2001,345:1378-1387. 被引量:1
  • 7National Institutes of Health. NIH consensus conference on the treatment of early-stage breast cancer. JAMA,1991,265:391-395. 被引量:1
  • 8Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med,2002,347: 1233-1241. 被引量:1
  • 9Liljegren G, Holmberg L, Bergh J, et al. 10-Year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: a randomized trial. J Clin Oncol,1999,17:2326-2333. 被引量:1
  • 10Renton SC, Gazet JC, Ford HT, et al. The importance of resection margin in conservative surgery for breast cancer. Eur J Surg Oncol,1996,22:17-22. 被引量:1

共引文献319

同被引文献47

  • 1刘敏,董丽华,王辉东,宋宇哲,刘百龙.乳腺癌保乳术后调强放疗与常规放疗参数的比较[J].中国老年学杂志,2014,34(11):2924-2926. 被引量:29
  • 2郭新峰,温泽淮,老膺荣,赖世隆.临床试验质量评价工具及其应用[J].中国循证医学杂志,2004,4(7):484-487. 被引量:34
  • 3张保宁.乳腺癌保乳手术的研究进展[J].中国普外基础与临床杂志,2005,12(3):204-206. 被引量:103
  • 4雷玉涛,赵红梅,侯宽永.乳腺导管原位癌临床诊治分析(附6例报告)[J].中国微创外科杂志,2005,5(10):871-872. 被引量:7
  • 5张保宁,邵志敏,乔新民,李波,姜军,杨名添,王水,宋三泰,张斌,杨红健.中国乳腺癌保乳治疗的前瞻性多中心研究[J].中华肿瘤杂志,2005,27(11):680-684. 被引量:247
  • 6Solin LJ,Fourquet A,Vicini FA,et al.Salvage treatment for local re-currence after breast-conserving surgery and radiation as initialtreatment for mammographically detected ductal carcinoma in situ of the breast[J].Cancer,2001,91(6): 1090-1097. 被引量:1
  • 7Cuzick J, Sestak I,Pinder SE,et al.Effeet of tamoxifen and radio- therapy in women with locally excised ductal carcinoma in situ:long-term results from the UK/ANZ DCIS trial[J].Lancet Oncol,2011,12(1):21-29. 被引量:1
  • 8Emdin SO,Granstrand B,Ringberg A.SweDCIS:radiotherapy after sector resection for duetal carcinoma in situ of the breast results of a randomised trial in a population offered mammography screening[J].Acta Oncol,2006,45(5):536-543. 被引量:1
  • 9Bijker N,Meijnen P, Peterse JL,et al.Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ:ten-year results of European Organisation for Research and Treatment of Cancer randomized phase Ⅲ trial 10853-a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group [J].J Clin Oncol,2006,24(21):3381-3387. 被引量:1
  • 10Group EBCC,Group ElL Bijker N,Meijnell P, et al.Breast- conserving treatmentth or without radiotherapy in ductal carcinoma in situ:ten-year results of European Organisation for Research and Treatment of Cancer randomized phase Ⅲ trial 1 0853 a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group[J].J Clin Oncol,2006,24(21):33 81-3387. 被引量:1

引证文献6

二级引证文献37

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部