摘要
目的探讨两种剂型硝酸咪康唑栓剂治疗经阴道手术前外阴阴道假丝酵母菌病(VVC)的疗效及对手术的影响。方法将吉林大学中日联谊医院门诊54例欲行经阴道手术的外阴阴道假丝酵母菌病患者分为两组,A组应用硝酸咪康唑栓剂400 mg治疗,B组应用硝酸咪康唑栓剂1200 mg治疗,对比两组疗效及对手术影响。结果两组首次治疗后总有效率分别为79.2%、83.3%,术后两组总有效率分别为87.5%、90.0%,差异无统计学意义;术后两组复发率分别为4.2%、6.7%,差异无统计学意义;A组治疗距手术平均时间15.25 d,B组治疗距手术平均时间6.5 d,差异有统计学意义。结论 1200 mg硝酸咪康唑栓治疗经阴道手术前VVC患者疗效确切,明显缩短治疗距手术平均时间,可作为治疗经阴道手术前VVC患者的首选用药。
OBJECTIVE To investigate the curative effect and the influence of operation of vulvovaginal candidiasis（VVC） treated with two forms of miconazole nitrate supositories before transvaginal operation.METHODS A total of 54 patients of VVC in China-Japan union hospital of Jilin University were divided into two groups.400 mg miconazole nitrate suppositories was used in group A,and 1200mg was used in group B.The curative effect and the influence of operation in two groups were compared.RESULTS The effective rates after first treatment of two groups were 79.2% and 83.3%;The effective rates after transvaginal operation were 87.5% and 90.0%;The recurrencerate of two groups were 4.2% and 6.7%.There were no significance differences between two groups.The average time of treatment to operation of group A was 15.25 days,and the average time of groups B was 6.5 days,the difference was statistically significant.CONCLUSION There′s precisely therapeutic effect of 1200 mg miconazole nitrate supositories to treat with patients of VVC who intended to take a transvaginal operation,it′ll shorten the time of the treatment to the operation.The 1200mg miconazole nitrate turunda should be the first adoption drug to treat the patients of VVC before transvaginal operation.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第15期3243-3244,共2页
Chinese Journal of Nosocomiology
