摘要
目的:研究淋巴结外 T 细胞性淋巴瘤( T- cell Lym phom a, T C L)中 Epstein- Barr 病毒( E B病毒)感染情况及其同 C D56 表达关系。方法:对15 例淋巴结反应性增生和33 例淋巴结外 T 细胞性淋巴瘤应用原位杂交法检测 E B E Rs 和免疫组织化学法检测表面抗原 C D56 的表达。结果:淋巴结外 T细胞性淋巴瘤中 E B E Rs和 C D56 表达率分别为 63.6% (21/33)和24.2% (8/33),淋巴结反应性增生中 E B E Rs 和 C D56 阳性表达率分别为 0% (0/15)和26.7% (4/15)。 E B E Rs 和 C D56 表达无相关性( P> 0.05)。结论:表明 E B病毒高度感染淋巴结外 T细胞性淋巴瘤,可能是其发生的一个重要因素,但 E B病毒感染同 C D56 表达无关。
Objective:To study the relationship between EBV infection and CD56 expression in the extranodal T-cell lymphomas (TCLs).Methods:33 cases of extranodal TCLs and 15 cases of reactive hyperplasia of lymphomas (RHs) were detected first with In situ hybridization for EBERs, and then with immunohistochemistry for CD56 expressions.Results:The positive rates of EBERs and CD56 in extranodal TCLs were 63.6%(21/33) and 27.3%(9/33) respectively, with no significant relationship (P>0.05).The Expression rate in RHs were o%(0/15) and 26.7%(4/15) respectively.Conclusion:The High EBV infection of extranodal TCLs may play an important role in the pathogenesis of TCLs , but it is not related to the expression of CD56.
出处
《郧阳医学院学报》
1999年第3期125-126,共2页
Journal of Yunyang Medical College