摘要
目的：了解本地区泌尿生殖道支原体感染及其对药物敏感性情况,为做好泌尿生殖道感染防治工作,指导临床合理用药提供实验依据。方法：对875例门诊NGU患者按试剂盒说明书采集标本进行支原体培养鉴定及药敏试验。结果：875例标本中支原体阳性386例,阳性率44.1%。其中Uu阳性率：36.2%（317/875）;Mh：1.9%（17/875）;Uu和Mh均阳性：6.0%（52/875）。男性感染率（33.0%）明显低于女性感染率（49.7%）;31岁~40岁年龄组的支原体培养阳性率达到最高峰（52.8%）。药敏结果显示：抗菌药物敏感率较高的是强力霉素、美满霉素,其次是交沙霉素、克拉霉素、阿齐霉素、罗红霉素;而耐药率较高的是氧氟沙星,其次是左旋氧氟沙星、司帕沙星。结论：Uu感染率高于Mh,女性感染率高于男性;处于性活跃期的人群感染率高;药敏结果提示强力霉素和美满霉素作为首选治疗药物。
Objective：To investigate mycoplasma infection of the urogenital tract and drug resistance for prevention of infection and to provide the experimental data for clinical medication.Methods： The samples from 875 NGU infected patients were collected and detected with mycoplasma kits according the instruction.Results： From 875 tested samples,the total positive percentage of Mycoplasma was 44.1%（386/875）,among these patients Uu was found 36.2%（317/875）,Mh 1.9%（17/875） and the mixed infection by Uu＋Mh 6.0%（52/875）.The positive percentage of Mycoplasma was found higher in women（49.7%） than men（33.0%）,and the infection rate reached the peak value（52.8%） in the age of 31~40 years.Drug sensitivity test showed that：mycoplasma was highly susceptible to Doxycycline and Minocin,next to Josamycin,Clarithromycin,Azithromycin and Roxithromyein,but highly resistant to Ofloxacin,and then Levofloxacin and Sparfloxacin.Conclusion： The infection rate of Uu was higher than Mh,we should pay more attention to women,whose infection rate were higher than man.There was also a high infection rate in the people of sex active stage.According the drug sensitivity test,we suggested that patients with mycoplasma infection should be preferentially treated with Doxycycline and Minocin.
出处
《中国卫生检验杂志》
CAS
2011年第6期1438-1439,1442,共3页
Chinese Journal of Health Laboratory Technology
关键词
非淋球菌性尿道炎
支原体培养
药敏试验
Non-gonococcal urethritis
Mycoplasma culture
Drug sensitivity test
