摘要
目的观察丹参酮ⅡA磺酸钠对肺心病患者血液流变学及血脂的影响。方法肺心病患者120例,随机分为观察组和对照组,每组各60例。对照组给予常规治疗;观察组在对照组基础上给予丹参酮ⅡA磺酸钠注射液,疗程14 d。比较治疗前后血液流变学指标和血脂变化。结果与对照组比较,治疗后观察组血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇均明显降低(P<0.05);全血黏度、血浆黏度等血流变学指标均有统计学差异(P<0.05)。结论丹参酮ⅡA磺酸钠能够调节血脂,改善血液流变学异常,对肺心病患者具有保护作用。
Purpose To observe the effect of tanshinone ⅡA sulfonate on hemorheology and blood lipid in patients with pulmonary heart disease.Methods 120 patients with pulmonary heart disease were randomly divided into observation group and control group,60 cases in each group.Control group was given the conventional treatment,while in observation group tanshinone ⅡA sulfonate injection was added on the basis of control group for a period of 14 d.Two groups′ changes of hemorheology index and blood lipid before and after operation were compared.Results Compared with control group,observation group′s serum total cholesterol,triglyceride and low density lipoprotein cholesterol were obviously decreased（P〈0.05）,the difference of hemorheology indexes such as whole blood viscosity and plasma viscosity had statistical significance（P〈0.05）.Conclusion Tanshinone ⅡA sulfonate can regulate blood lipid,improve hemorheology abnormality and produce protective effect on patients with pulmonary heart disease.
出处
《中国生化药物杂志》
CAS
CSCD
北大核心
2011年第3期237-238,共2页
Chinese Journal of Biochemical Pharmaceutics
