摘要
目的 检测空腹血糖正常的高血压患者的糖代谢状态,为全面干预危险因素提供科学依据.方法 对46例高血压患者、40例血压正常者做口服葡萄糖耐量试验（OGTT）,并同步测定血清胰岛素浓度.结果 高血压组OGTT检出糖耐量减低和2型糖尿病的发生率分别为28.3%和8.7%,糖代谢异常发生率与血压正常组相比差异有统计学意义（P＜0.05）.高血压组和血压正常组的胰岛素抵抗指数分别为1.2±0.3和1.0±0.4,差异有统计学意义 （P＜0.01）.结论 以OGTT同步测定血清胰岛素浓度的方法来检测高血压患者的糖代谢状态,不仅可使部分2型糖尿病和糖耐量减低患者得以早期诊断,而且可初步评估患者胰岛素敏感性及胰岛素抵抗程度,具有重要临床意义.
Objective To detect the state of glucose metabolism of hypertensive patients with normal fasting glucose, risk factors for a comprehensive intervention to provide a scientific basis. Methods 46 patients with hypertension and 40 patients with normal blood pressure received oral glucose tolerance test （OGqq＇）, Simultane- ous determination of serum insulin concentrations. Results OGTT detected impaired glucose tolerance and type 2 diabetes incidence rates were 28.3% and 8.7%, compared with the control group were significantly different （P〈 0.05 ）. HOMA-IR in hypertension group and control group were 1.2±0.3 and 1.0±0.4, there was a significant dif- ference （P〈0.01）. Conclusion Detecting the state of glucose metabolism of hypertensive patients with OGTT and simultaneous determinationing of serum insulin concentrations, not only may help early diagnosis type 2 diabetes incidence and impaired glucose tolerance, but also help to preliminary evluate insulin sensitivity and insulin resistance degree of hypertension patients.
出处
《中国心血管病研究》
CAS
2011年第5期351-353,共3页
Chinese Journal of Cardiovascular Research
关键词
高血压
血糖
葡萄糖耐量试验
Hypertension
Blood glucose
Glucose tolerance test
