摘要
目的:研究子宫内膜异位症患者血清脂联素、胰岛素样生长因子-1(IGF-1)水平的变化及其与体重指数的相关性。方法:选取2009年入住我院的45例子宫内膜异位症患者作为观察组,30例健康体检妇女作为对照组。观察所有研究对象的血清脂联素(APN)、胰岛素样生长因子-1水平及其体重指数(BM I)。结果:与对照组比较,观察组患者血清APN水平及BM I值降低(P<0.05),血清IGF-1水平升高(P<0.05);与观察组早期比较,观察组晚期患者血清APN水平及BM I值降低(P<0.05),血清IGF-1水平升高(P<0.05);观察组患者的BM I值与其血清IGF-1水平呈负相关(r=-0.693,P<0.05),与其血清APN水平呈正相关(r=0.889,P<0.05)。结论:血清脂联素、胰岛素样生长因子-1水平在子宫内膜异位症的发病机制中有一定作用,且患者的低体重指数可能与其血清胰岛素样生长因子-1、脂联素水平的变化有关。
Objective：To study the serum level change of Adiponectin（APN）,IGF-1 in endometriosis and correlation between them and body mass index（BMI）.Methods：45 cases of endometriosis patients who were in our hospital childbirth during 2009 were selected as observation group.30 cases of healthy check-up women were selected as control group.The level of APN,IGF-1 and their BMI were observe.Results：Compared with control group,the observation group＇s serum APN level and BMI were lower（P0.05）,and serum IGF-1 level was higher（P 0.05）.Compared with the early observation group,the late observation group＇s serum APN level and BMI were lower（P0.05）,serum IGF-1 level was higher（P0.05）.The observation group＇s BMI value and serum IGF-1 level negatively correlated（r=-0.693,P0.05）,and the observation group＇s BMI value and serum IGF-1 level positively correlated（r= 0.889,P0.05）.Conclusion：The serum level of APN,IGF-1 has certain effect in the pathogenesis of endometriosis,and the low BMI of patients may be relative with the change of serum IGF-1,APN levels.
出处
《中国妇幼保健》
CAS
北大核心
2011年第14期2119-2120,共2页
Maternal and Child Health Care of China
