摘要
代谢组学是继基因组学、转录组学和蛋白质组学之后新近发展起来的一门学科,作为后基因时代的一种全新的组学技术,代谢组学以系统生物学为理论基础,以生物体液为研究对象,以现代谱学分析技术为支撑,对生物体内低分子量化学组分进行多维多息分析,最终以明晰机体生物学变化本质为目的。代谢组学近年来发展迅速,广泛应用于中医药研究领域,为研究中医药复杂理论体系提供了新的思路和研究平台。文章通过论述代谢组学用于中医药复杂理论体系中的中医藏象、中医证候、中医体质、中药复方等理论,充分显示出代谢组学在中医药复杂理论体系研究中的优势及广阔的前景。
With the advent of post-genomic era,metabonomics become the major subject after genomics,proteomics and transcriptomics.Metabonomics theoretical based on system biology,aim at biofluid,analyse low molecular chemistry components in living organisms with spectral analysis technology,finally find the essence of biological changes.In recent years,metabonomics have developed quickly and it is used widely the field of TCM.It provides a new idea and method for complicated theory system research of TCM.This article discussed application of metabonomics in the research of TCM including theories of visceral manifestation,syndrome,constitution and Chinese herbal compound.We believe,metabonomics could play a very important role in the study of TCM and have his clear advantage and broad prospect.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2011年第5期993-998,共6页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家重点基础研究发展计划(973计划)课题(No.2009CB522707)
武汉市晨光计划(No.201050231081)~~
关键词
代谢组学
中医药复杂理论体系
藏象理论
证候
体质
中药复方
Metabonomics
Complicated theory system of TCM
Theory of visceral manifestation
Syndrome
Constitution
Chinese herbal compound
