摘要
目的:探讨无症状性前列腺炎对精液参数的影响。方法:对已诊断无症状前列腺炎的152例患者按EPS中的WBC水平进行分组:A组(WBC+～++)和B组(WBC+++～++++);并设立健康正常的个体作为对照组(C组)。检测指标包括:精液量、pH值、液化时间、精子浓度、精子存活率、a级精子百分率、正常形态精子百分率、WBC计数与相关的炎症细胞因子等。结果:精液参数中液化时间、a级精子百分率(%)和正常形态精子百分率(%):A组(24.5±5.2)min、(20.0±4.1)、(10.5±4.8)和B组(30.4±5.0)min、(10.0±3.8)、(7.5±4.2)与C组(18.5±5.3)min、(32.3±4.5)、(17.8±3.6)相比,以及B组与A组相比,差异均有显著性(P<0.001),而pH值、精液量、精子存活率、精子浓度:A组(7.6±0.3)、(3.0±1.1)ml、(56.0±6.0)%、(65.9±11.3)×106/ml,B组(7.7±0.3)、(2.8±1.2)ml、(52.3±6.3)%、(62.5±10.3)×106/ml和C组(7.5±0.2)、(2.9±1.2)ml、(62.1±5.3)%、(87.7±10.1)×106/ml差异均无显著性(P>0.05)。B组精液中IL-1β(58.64±30.82)pg/ml、TNF-α(50.57±27.48)pg/ml与C组IL-1β(17.68±5.65)pg/ml、TNF-α(23.50±4.80)pg/ml比较,显著上升(P<0.001)。结论:无症状性前列腺炎对精液主要参数有明显影响。
Objectives：To study the impact of asymptomatic prostatitis on semen parameters.Method：Based on the count of WBC in EPS,we assigned 152 patients with asymptomatic（type IV） prostatitis to Groups A（WBC ＋ to ＋＋） and B（WBC ＋＋＋ to ＋＋＋＋）,and included 68 normal healthy men controls in Group C.All the patients were examined for the volume,pH value and liquefaction time of the semen,sperm concentration,sperm survival rate,grade a sperm percentage,morphologically normal sperm percentage,WBC count,and accompanying inflammatory cytokines.Results：The semen liquefaction time,grade a sperm percentage and morphologically normal sperm percentage were（24.5±5.2） min,20.0±4.1 and 10.5±4.8 in Group A,（30.4±5.0） min,10.0±3.8 and 7.5±4.2 in Group B,and（18.5±5.3） min,32.3±4.5 and 17.8±3.6 in Group C,with statistically significant differences between A and B（P0.01）.The pH value,semen volume,sperm survival rate and sperm concentration were 7.6±0.3,（3.0±1.1） ml,56.0±6.0 and（65.9±11.3）×106/ml in Group A,7.7±0.3,（2.8±1.2） ml,52.3±6.3 and（62.5±10.3）×106/ml in Group B,and 7.5±0.2,（2.9±1.2） ml,62.1.0±5.3 and（87.7±10.1）×106/ml in Group C,with no significant differences among the three groups（P0.05）.The contents of interleukin-1β（IL-1β） and tumor necrosis factor-α（TNF-α） in the semen were（58.64±30.82） pg/ml and（50.57±27.48） pg/ml in Group B,significantly increased as compared with（17.68±5.65） pg/ml and（23.50±4.80） pg/ml in Group C（P0.01） Conclusion：Asymptomatic prostatitis effects significant changes in the major parameters of the patient＇s semen quality.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2011年第3期257-260,共4页
National Journal of Andrology
