摘要
目的:探讨无症状性前列腺炎(NIH-IV)对血PSA的影响。方法:选择常规体检男性242例,慢性前列腺炎症状评分(CPSI)指数评分<8分。患者前列腺指诊及尿液分析未见异常,检查前先抽血查PSA,取前列腺按摩液(EPS)行白细胞计数,评估Ⅳ型前列腺炎发病情况,比较Ⅳ型前列腺炎及对照组的血PSA水平,并分析Ⅳ型前列腺炎患者EPS中白细胞的数目与PSA升高的相关性。结果:在242例体检男性中,Ⅳ型前列腺炎的发病率为34.3%(83/242)。Ⅳ型前列腺炎组与对照组间的年龄、前列腺体积差异无统计学意义(P>0.05),而PSA在Ⅳ型前列腺炎组为(2.88±2.60)μg/L,显著高于对照组(1.59±1.76)μg/L(P<0.05)。Ⅳ型前列腺炎组中PSA≥4μg/L的比例为13.3%(11/83),而对照组中PSA≥4μg/L的比例为4.4%(7/159),两者差异有统计学意义(P<0.05)。Ⅳ型前列腺炎患者EPS中白细胞数目多少与PSA的高低并无统计学意义(P>0.05)。结论:Ⅳ型前列腺炎亦是血PSA升高的原因之一。
Objective：To evaluate the prevalence and relationship of serum prostate specific antigen （PSA） levels in a screening population of men diagnosed with asymptomatic prostatic inflammation （NIH category Ⅳ prostatitis）. Methods,.During June 2004 and March 2005, 242 men with normal DRE and normal urinalysis were randomly selected from our out-patient department to be evaluated for NIH category Ⅳ prostatitis. Severity of symptoms was scored by the NIH Chronic Prostatitis Symptom Index in men whose scores were no more than 8. All participants had a serum sample obtained for PSA before examination. Patients were stratified into categorie IV prostati- tis according to WBC counts on examination of the expressed prostatic secretions（EPS）. The levels of PSA were compared between men with or without evidence of prostatitis on EPS. Associations between the levels of PSA and leukocyte counts in patients diagnosed as prostatitis were assessed using Pearson correlation tests, Results： The prevalence of NIH category Ⅳ prostatitis was 34.3% （83 of 242 cases） in participants. The mean levels of PSA were 2. 88 ng/ml for NIH-Ⅳ prostatitis which was significantly higher than those without prostatitis （mean PSA 1.59）, The percentage of abnormal participants with PSA levels over 4ng/ml was differed significantly between men with evidence of prostatitis（13.3%） and without（4, 4%）. The levels of PSA and leukocyte counts seems no apparent correlation in between, Conclusions：These data suggest that category Ⅳ prostatitis is fairly prevalent among men in the general population. Screening for NIH category Ⅳ prostatitis should be considered in some men with elevated PSA,
出处
《临床泌尿外科杂志》
2006年第3期180-182,共3页
Journal of Clinical Urology
基金
广东省科技计划项目(2004B30301013)
关键词
前列腺炎
前列腺特异抗原
Chronic prostatitis
Prostate specific antigen
