摘要
目的观察局部热疗联合胸腔灌注顺铂治疗恶性胸腔积液的临床疗效及毒副反应。方法 42例恶性胸腔积液随机分为两组,治疗组21例给予局部热疗联合胸腔灌注顺铂治疗;对照组21例仅给予胸腔灌注顺铂治疗。结果治疗组有效率较对照组明显提高(P<0.05)。两组毒副反应均较少。结论局部热疗联合胸腔灌注顺铂治疗恶性胸腔积液近期疗效较好,毒副反应较轻。
Objective To observe the effect and toxicity of local thermotherapy combined with intrathoracic infusion by cisplatin in the treatment of malignant pleural effusion （MPE）. Methods All the 42 patients with MPE were randomly divided into two groups. Twenty one patients in the treatment group were treated with local thermotherapy combined with intrathoracie infusion by cisplatin, 21 patients in the control group were treated with intrathoraeic infusion by cisplatin. Results The response rate in the treatment group was higher than that in the con- trol group （P 〈 0.05 ）. In the two groups, the toxicities were less. Conclusions Local thermotherapy combined with intrathoracic infusion by cisplatin is effective in the treatment of patients with MPE. The toxicities are slight.
出处
《肿瘤基础与临床》
2011年第1期41-42,共2页
journal of basic and clinical oncology
关键词
胸腔灌注
顺铂
局部热疗
恶性胸腔积液
intrathoracic infusion
cisplatin
local thermotherapy
malignant pleural effusion
