期刊文献+

热疗联合胸腔灌注化疗药物治疗恶性胸腔积液临床观察 被引量:8

下载PDF
导出
摘要 目的观察热疗联合胸腔灌注化疗药物治疗恶性胸腔积液的疗效、毒副反应和患者的生活质量。方法58例确诊的晚期肺癌合并恶性胸腔积液的患者,分为热疗联合胸腔灌注组即A组和单纯胸腔灌注组B组,A组:盐水50ml+顺铂60mg胸腔灌注d1d8,胸腔灌注30min内采用W2102型高频治疗仪行深部热疗,每周两次。B组:盐水50ml+顺铂60mg胸腔灌注d1d8,不联合热疗。结果A组有效率为86.2%,B组有效率为62.1%,两组比较差异有统计学意义,P<0.05,毒副反应轻微,可耐受。两组生活质量好转率分别为75.86%和48.28%,两组比较差异有统计学意义,P<0.05。结论采用热疗联合胸腔灌注化疗药物治疗恶性胸腔积液有效率高,不良反应可耐受,生活质量提高。
出处 《疾病监测与控制》 2010年第2期92-93,共2页 Journal of Diseases Monitor and Control
  • 相关文献

参考文献5

二级参考文献47

  • 1陈正东 孙燕 王肇为.实用肿瘤并发症诊断治疗[M].合肥:安徽科学技术出版社,1997.146. 被引量:7
  • 2van der Zee J. Heating the patient : a promising approach. Ann Oncol, 2002,13(8) : 1173-1184. 被引量:1
  • 3Takahashi I, Emi Y, Hasuda S, et al. Clincal application of hyperthernfia combined with anticancer drugs for the treatment of solid tumors. Surgery, 2002,131 (1 Suppl) : S78-S84. 被引量:1
  • 4Westermann AM, Grosen EA, Katschinski DM, et al. A pilot study of whole body hyperthermia and carboplatin in platinum-resistant ovarian cancer. Eur J Cancer, 2001, 37(9) : 1111-1117. 被引量:1
  • 5Rietbroek RC, van de Vaart PJ, Haveman J, et al. Hyperthermia enhances the cytotoxicity and platinum-DNA adduct formation of lobaplatin and oxaliplatin in cultured SW1573 cells. J Cancer Res Clin Oncol, 1997, 123(1): 6-12. 被引量:1
  • 6Hirohashi Y, Hidaka K, Sato S, et al. Biomodulation by hyperthermia of topoisomeraes II-targeting drug in human colorectal cancer cells. Jpn J Cancer Res, 1995, 86(11): 1097-1105. 被引量:1
  • 7Van Heek-Romanowski R, Putter S, Trarbach T, et al. Etoposide toxicity on human neuroblastoma cells in vitro is enhanced by preceeding hyperthermia. Med Pediatr Oncol,2001,36( 1 ) : 197-198. 被引量:1
  • 8Kondo T, Ueda K, Kano E. Combined effects of hyperthermia and CPT-11 on DNA strand breaks in mouse rnmammry carcinoma FM3A cells. Anticancer Res, 1995,15 ( 1 ) : 83-86. 被引量:1
  • 9Nishida Y, Hamaji M, Miyazaki S, et al. Thermochernotherapy using low dose CPT-11 in a patient with local recurrence of rectal cancer. Gan To Kagaku Ryoho, 1999,26(4) :549-552. 被引量:1
  • 10Van Bree C, Beumer C, Rodermond HM, et al. Effectiveness of 2', 2' difluorodeoxycytidine (Gemcitabine) combined with hyperthermia in rat R-1 rhabdomyosarcoma in vitro and in vivo. Im J Hyperthermia, 1999,15(6) : 549-556. 被引量:1

共引文献158

同被引文献57

引证文献8

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部