摘要
骨质疏松是一种严重影响人类生命健康的疾病,其发病率逐年增加。并且骨质疏松症易致骨折。褪黑素具有抑制破骨细胞的骨吸收作用,促进成骨细胞分化,同时,其能间接通过对其他激素和细胞因子的刺激来促进骨量增加。并且,褪黑素在多项影响骨质疏松动物模型的骨代谢研究中均取得了良好的治疗效果。因其具有实用价值,本文就其研究进展做一综述。
Osteoporsis is a serious disease that influence on the human＇s health, which is getting more and more year by year. Moreover, osteoporosis can easily cause fracture. Melatonin can restrain osteoclast resorption as well as promote osteoblast differentiation. Meantime, it can accelerate bone mass increasing via indirectly stimulation of other hormone and cytokin, in addition, melatonin has splendid effects in the treatment of animal model of osteoporsis of bone metabolism. Progress of effect of melatonin on senile osteoporsis of bone metabolism was reviewed due to its practical value.
出处
《中国骨质疏松杂志》
CAS
CSCD
2011年第2期176-180,共5页
Chinese Journal of Osteoporosis
