摘要
目的:观察芒果苷单钠盐的抑菌作用。方法:以咽喉及上呼吸道常见致病菌肺炎双球菌、肺炎克雷伯菌、金黄色葡萄球菌和流感嗜血杆菌为受试菌,分别通过体外抑菌和体内抑菌实验来观察芒果苷单钠盐的抑菌作用。结果:体外研究显示芒果苷单钠盐对肺炎双球菌、肺炎克雷伯菌、金黄色葡萄球菌和流感嗜血杆菌均表现出一定的抑制作用。其最小抑菌质量浓度分别为10.0,5.0,10.0,2.5 g·L-1。体内研究显示芒果苷单钠盐可显著提升菌液感染小鼠的存活率。结论:芒果苷单钠盐具有明显的抑菌作用。
Objective:To investigate the bacteriostatic action of mangoferin monosodium salt.Method:Bacteriostasis in vivo and in vitro experiments for Diplococcus pennmoniae,Klebsiella pneumoniae,Staphylococcus aureus,Haemophilus influenzae was examined respectively to observe the antibiosis effect of mangoferin monosodium salt.Result:Mangoferin monosodium salt showed some extents of antibiosis effect to D.pennmoniae,K.pneumoniae,S.aureus,H.influenzae for in vitro experiment.The minimal inhibitory concentration(MIC) were 10.0,5.0,10.0,2.5 g·L^-1,respectively.Mangoferin monosodium salt also showed significant in vivo protection effect in infected mouse.Conclusion:Mangoferin monosodium salt has good bacteriostatic action.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第6期173-175,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
广西应用基础研究专项(0731054)
广西青年基金资助项目(0640052)
广西教育厅资助项目(200507049)
关键词
芒果苷单钠盐
抑菌作用
肺炎双球菌
肺炎克雷伯菌
金黄色葡萄球菌
流感嗜血杆菌
mangoferin monosodium salt; bacteriostati action; Diplococcus pennmoniae; Klebsiella pneumoniae; Staphylococcus aureus; Haemophilus influenzae;