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芒果苷单钠盐的抑菌作用研究 被引量:7

Bacteriostatic Action of Mangoferin Monosodium Salt
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摘要 目的:观察芒果苷单钠盐的抑菌作用。方法:以咽喉及上呼吸道常见致病菌肺炎双球菌、肺炎克雷伯菌、金黄色葡萄球菌和流感嗜血杆菌为受试菌,分别通过体外抑菌和体内抑菌实验来观察芒果苷单钠盐的抑菌作用。结果:体外研究显示芒果苷单钠盐对肺炎双球菌、肺炎克雷伯菌、金黄色葡萄球菌和流感嗜血杆菌均表现出一定的抑制作用。其最小抑菌质量浓度分别为10.0,5.0,10.0,2.5 g·L-1。体内研究显示芒果苷单钠盐可显著提升菌液感染小鼠的存活率。结论:芒果苷单钠盐具有明显的抑菌作用。 Objective:To investigate the bacteriostatic action of mangoferin monosodium salt.Method:Bacteriostasis in vivo and in vitro experiments for Diplococcus pennmoniae,Klebsiella pneumoniae,Staphylococcus aureus,Haemophilus influenzae was examined respectively to observe the antibiosis effect of mangoferin monosodium salt.Result:Mangoferin monosodium salt showed some extents of antibiosis effect to D.pennmoniae,K.pneumoniae,S.aureus,H.influenzae for in vitro experiment.The minimal inhibitory concentration(MIC) were 10.0,5.0,10.0,2.5 g·L^-1,respectively.Mangoferin monosodium salt also showed significant in vivo protection effect in infected mouse.Conclusion:Mangoferin monosodium salt has good bacteriostatic action.
出处 《中国实验方剂学杂志》 CAS 北大核心 2011年第6期173-175,共3页 Chinese Journal of Experimental Traditional Medical Formulae
基金 广西应用基础研究专项(0731054) 广西青年基金资助项目(0640052) 广西教育厅资助项目(200507049)
关键词 芒果苷单钠盐 抑菌作用 肺炎双球菌 肺炎克雷伯菌 金黄色葡萄球菌 流感嗜血杆菌 mangoferin monosodium salt; bacteriostati action; Diplococcus pennmoniae; Klebsiella pneumoniae; Staphylococcus aureus; Haemophilus influenzae;
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